Acquisition of neurodegenerative features in isogenic OPTN(E50K) human stem cell-derived retinal ganglion cells associated with autophagy disruption and mTORC1 signaling reduction
同源 OPTN(E50K) 人类干细胞衍生的视网膜神经节细胞的神经退行性特征的获得与自噬破坏和 mTORC1 信号传导减少有关
期刊:Acta Neuropathologica Communications
影响因子:6.2
doi:10.1186/s40478-024-01872-2
Kang-Chieh Huang, Cátia Gomes, Yukihiro Shiga, Nicolas Belforte, Kirstin B VanderWall, Sailee S Lavekar, Clarisse M Fligor, Jade Harkin, Shelby M Hetzer, Shruti V Patil, Adriana Di Polo, Jason S Meyer0