Personalized pharmacokinetic-pharmacodynamic guided therapy via an induced pluripotent stem cell-derived multi-organoid platform in NF1-mutant breast cancer.
在 NF1 突变型乳腺癌中,通过诱导多能干细胞衍生的多器官类器官平台进行个性化药代动力学-药效学指导治疗。
期刊:Signal Transduction and Targeted Therapy
影响因子:52.7
doi:10.1038/s41392-026-02595-7
Lim Jung Hwa, Mun Seon Ju, Kang Hyun Mi, Yu Won Dong, Oh Soo Jin, Lee Ji-Yoon, Son Ye Seul, Lee Sugi, Kim Dae Soo, Lee Jaeseo, Kim Su Jeong, Cho Hyun-Soo, Son Myung Jin, Son Mi-Young, Jung Cho-Rok