日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Itacitinib for prevention of graft-versus-host disease and cytokine release syndrome in haploidentical transplantation

伊他替尼用于预防单倍体移植中的移植物抗宿主病和细胞因子释放综合征

Abboud, Ramzi; Schroeder, Mark A; Rettig, Michael P; Jayasinghe, Reyka G; Gao, Feng; Eisele, Jeremy; Gehrs, Leah; Ritchey, Julie; Choi, Jaebok; Abboud, Camille N; Pusic, Iskra; Jacoby, Meagan; Westervelt, Peter; Christopher, Matthew; Cashen, Amanda; Ghobadi, Armin; Stockerl-Goldstein, Keith; Uy, Geoffrey L; DiPersio, John F

BI-5756 Reduces Graft-Versus-Host Disease Through CB1-Mediated Treg Upregulation

BI-5756 通过 CB1 介导的 Treg 上调来减轻移植物抗宿主病

Sena Kim ,Abdul-Jalil Dania ,Sora Lim ,Jaebok Choi

Novel JAK Inhibitors to Reduce Graft-Versus-Host Disease after Allogeneic Hematopoietic Cell Transplantation in a Preclinical Mouse Model

新型 JAK 抑制剂可减少临床前小鼠模型中异基因造血细胞移植后的移植物抗宿主病

Sena Kim, Peter Ruminski, Megh Singh, Karl Staser, Kidist Ashami, Julie Ritchey, Sora Lim, John F DiPersio, Jaebok Choi

HSPA9/mortalin inhibition disrupts erythroid maturation through a TP53-dependent mechanism in human CD34+ hematopoietic progenitor cells

HSPA9/mortalin 抑制通过 TP53 依赖性机制破坏人类 CD34+ 造血祖细胞中的红细胞成熟

Christopher Butler, Morgan Dunmire, Jaebok Choi, Gabor Szalai, Anissa Johnson, Wei Lei, Xin Chen, Liang Liu, Wei Li, Matthew J Walter, Tuoen Liu

S100A9 upregulated by IFNGR signaling blockade functions as a novel GVHD suppressor without compromising GVL in mice

IFNGR信号通路阻断上调S100A9,使其在小鼠体内发挥新型GVHD抑制因子的作用,且不影响GVL效应。

Kim, Sena; Lim, Sora; Kim, Boram; Ritchey, Julie; Vij, Kiran; Prior, Julie; Marsala, Lynne; Stoner, Alyssa; Gao, Feng; Achilefu, Samuel; Cooper, Matthew L; DiPersio, John F; Choi, Jaebok

A Multicenter Phase 2 Clinical Trial of 10-Day Decitabine, Dose-Escalated Donor Lymphocyte Infusion, and Ruxolitinib for Relapsed Acute Myeloid Leukemia and Myelodysplastic Syndromes after Allogeneic Hematopoietic Cell Transplantation

一项多中心 II 期临床试验,研究 10 天地西他滨、剂量递增的供体淋巴细胞输注和鲁索替尼治疗异基因造血干细胞移植后复发性急性髓系白血病和骨髓增生异常综合征的疗效

Rashidi, Armin; Huselton, Eric J; Stefanski, Heather E; DeFor, Todd E; Shanley, Ryan; Choi, Jaebok; DiPersio, John F; Juckett, Mark; Miller, Jeffrey S; Weisdorf, Daniel J; Schroeder, Mark A

Phase I-II Trial of Early Azacitidine after Matched Unrelated Donor Hematopoietic Cell Transplantation

匹配无关供者造血干细胞移植后早期应用阿扎胞苷的I/II期试验

Xu, Ziheng; Choi, Jaebok; Cooper, Matthew; King, Jeffrey; Fiala, Mark A; Liu, Jingxia; Pusic, Iskra; Romee, Rizwan; Cashen, Amanda; Jacoby, Meagan A; Stockerl-Goldstein, Keith; Abboud, Camille; Vij, Ravi; Uy, Geoffrey; Westervelt, Peter; Walter, Matthew J; DiPersio, John F; Schroeder, Mark A

The adrenal stress response is an essential host response against therapy-induced lethal immune activation

肾上腺应激反应是抵抗治疗引起的致命免疫激活的重要宿主反应

Ling Guo, Weinan Wang, Qian Wang, Dan Hao, Misa Ito, Bin Huang, Chieko Mineo, Philip W Shaul, Jaebok Choi, L Frank Huang, Xiang-An Li

Baricitinib prevents GvHD by increasing Tregs via JAK3 and treats established GvHD by promoting intestinal tissue repair via EGFR

巴瑞替尼通过JAK3途径增加调节性T细胞(Tregs)来预防移植物抗宿主病(GvHD),并通过EGFR途径促进肠道组织修复来治疗已发生的GvHD。

Kim, Sena; Ashami, Kidist; Lim, Sora; Staser, Karl; Vij, Kiran; Santhanam, Srikanth; Ritchey, Julie; Peterson, Sarah; Gao, Feng; Ciorba, Matthew A; Cooper, Matthew L; DiPersio, John F; Choi, Jaebok

Antibody-drug conjugates plus Janus kinase inhibitors enable MHC-mismatched allogeneic hematopoietic stem cell transplantation

抗体-药物偶联物加 Janus 激酶抑制剂可实现 MHC 不匹配的异基因造血干细胞移植

Stephen P Persaud, Julie K Ritchey, Sena Kim, Sora Lim, Peter G Ruminski, Matthew L Cooper, Michael P Rettig, Jaebok Choi, John F DiPersio