日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Combining mechanistic modeling with machine learning as a strategy to predict inflammatory bowel disease clinical scores

将机制建模与机器学习相结合,作为预测炎症性肠病临床评分的策略

Shim, Jaehee V; Rehberg, Markus; Wagenhuber, Britta; van der Graaf, Piet H; Chung, Douglas W

Predicting individual-specific cardiotoxicity responses induced by tyrosine kinase inhibitors

预测酪氨酸激酶抑制剂引起的个体特异性心脏毒性反应

Shim, Jaehee V; Xiong, Yuguang; Dhanan, Priyanka; Dariolli, Rafael; Azeloglu, Evren U; Hu, Bin; Jayaraman, Gomathi; Schaniel, Christoph; Birtwistle, Marc R; Iyengar, Ravi; Dubois, Nicole C; Sobie, Eric A

Transcriptomic profiling of human cardiac cells predicts protein kinase inhibitor-associated cardiotoxicity

人类心脏细胞的转录组分析可预测蛋白激酶抑制剂相关的心脏毒性

J G Coen van Hasselt #, Rayees Rahman #, Jens Hansen, Alan Stern, Jaehee V Shim, Yuguang Xiong, Amanda Pickard, Gomathi Jayaraman, Bin Hu, Milind Mahajan, James M Gallo, Joseph Goldfarb, Eric A Sobie, Marc R Birtwistle, Avner Schlessinger, Evren U Azeloglu, Ravi Iyengar

RNase III nucleases from diverse kingdoms serve as antiviral effectors

来自不同王国的 RNase III 核酸酶可作为抗病毒效应物

Lauren C Aguado, Sonja Schmid, Jared May, Leah R Sabin, Maryline Panis, Daniel Blanco-Melo, Jaehee V Shim, David Sachs, Sara Cherry, Anne E Simon, Jean-Pierre Levraud, Benjamin R tenOever

I love it when a plan comes together: Insight gained through convergence of competing mathematical models

我喜欢计划最终成型的那种感觉:通过相互竞争的数学模型的融合而获得的洞见。

Gong, Jingqi Q X; Shim, Jaehee V; Núñez-Acosta, Elisa; Sobie, Eric A

Mechanistic Systems Modeling to Improve Understanding and Prediction of Cardiotoxicity Caused by Targeted Cancer Therapeutics

利用机制系统建模来提高对靶向癌症治疗药物引起的心脏毒性的理解和预测

Shim, Jaehee V; Chun, Bryan; van Hasselt, Johan G C; Birtwistle, Marc R; Saucerman, Jeffrey J; Sobie, Eric A

microRNA Function Is Limited to Cytokine Control in the Acute Response to Virus Infection

microRNA的功能仅限于病毒感染急性反应中的细胞因子调控

Aguado, Lauren C; Schmid, Sonja; Sachs, David; Shim, Jaehee V; Lim, Jean K; tenOever, Benjamin R

Drosha as an interferon-independent antiviral factor

Drosha 是一种不依赖干扰素的抗病毒因子

Shapiro, Jillian S; Schmid, Sonja; Aguado, Lauren C; Sabin, Leah R; Yasunaga, Ari; Shim, Jaehee V; Sachs, David; Cherry, Sara; tenOever, Benjamin R

The Mammalian response to virus infection is independent of small RNA silencing

哺乳动物对病毒感染的反应与小RNA沉默无关。

Backes, Simone; Langlois, Ryan A; Schmid, Sonja; Varble, Andrew; Shim, Jaehee V; Sachs, David; tenOever, Benjamin R