Somatic cancer variants enriched in Alzheimer's disease microglia-like cells drive inflammatory and proliferative states
富集于阿尔茨海默病小胶质细胞样细胞中的体细胞癌变异会驱动炎症和增殖状态
期刊:Cell
影响因子:42.5
doi:10.1016/j.cell.2026.03.040
Huang, August Yue; Zhou, Zinan; Talukdar, Maya; Enyenihi, Liz; Miller, Michael B; Chhouk, Brian; Rosen, Ila; Zheng, Mengyue; Zhou, Minye; Yang, Averill; Stronge, Edward; Durens, Madel; Nguyen, Minh; Choi, Jaejoon; Zhao, Boxun; Khoshkhoo, Sattar; Kim, Junho; Andersen, Rebecca; An, Zheming; Cheng, Yuchen; Ganz, Javier; Mekerishvili, Levan; Travaglini, Kyle J; Gabitto, Mariano I; Hodge, Rebecca D; Kaplan, Eitan S; Belk, Julia A; Landau, Dan; Lein, Ed S; De Jager, Philip L; Bennett, David A; Marro, Samuele G; Papapetrou, Eirini P; Lee, Eunjung Alice; Walsh, Christopher A
胶质细胞
肿瘤
炎症
阿尔茨海默症
细胞生物学
肿瘤免疫
炎症/感染
