日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Emerging roles for endothelial mineralocorticoid receptor in disease pathogenesis: potential new indications for mineralocorticoid receptor antagonism

内皮细胞盐皮质激素受体在疾病发病机制中的新兴作用:盐皮质激素受体拮抗剂的潜在新适应症

An, Wenxi; Jaffe, Iris Z

Distinct endothelial cell toxicities of Abl tyrosine kinase inhibitors lead to arterial thrombosis

Abl酪氨酸激酶抑制剂对内皮细胞的不同毒性会导致动脉血栓形成

Travers, Richard; Stepanian, Alec; Redford, Sebastiana; Martin, Gregory; Svedberg, Nicole L; Xu, Kun; Merrill-Skoloff, Glenn; Chen, Christopher; Flaumenhaft, Robert; Jaffe, Iris Z

Smooth muscle cell estrogen receptor alpha promotes arterial stiffness in the absence of estradiol

平滑肌细胞雌激素受体α在缺乏雌二醇的情况下促进动脉僵硬

Turner, Casey G; Matz, Jacqueline; Breton, Jade; de Oliveira, Karla C; Kenney, Rachel; Vorn, Jennifer; Zhao, Michelle; Ibarrola, Jaime; Lu, Qing; Martin, Gregory; Sun, Zhe; Jaffe, Iris Z; Hill, Michael A; DuPont, Jennifer J

The angiotensin II type 2 receptor attenuates aging-associated arterial stiffness in female mice

血管紧张素II 2型受体可减轻雌性小鼠衰老相关的动脉僵硬

Turner, Casey G; Kenney, Rachel; Vorn, Jennifer; Kim, Seung Kyum; Martin, Greg; Pulakat, Lakshmi; Jaffe, Iris Z; DuPont, Jennifer J

Rapamycin reduces mineral density and promotes beneficial vascular remodeling in a murine model of severe medial arterial calcification.

雷帕霉素可降低小鼠严重中层动脉钙化模型中的矿物质密度,并促进有益的血管重塑

Behzadi Parya, Wendling Andrew A, Cuevas Rolando A, Crane Alex, Chu Claire C, Moorhead William J 3rd, Wong Ryan, Brown Mark, Tamakloe Joshua, Suresh Swathi, Salehi Payam, Jaffe Iris Z, Kuipers Allison L, Lukashova Lyudmila, Verdelis Konstantinos, St Hilaire Cynthia

Mineralocorticoid and estrogen receptors as sex-dependent modulators of vascular health in aging and obesity

盐皮质激素受体和雌激素受体作为衰老和肥胖过程中血管健康的性别依赖性调节因子

Turner, Casey G; de Oliveira, Karla; Jaffe, Iris Z; DuPont, Jennifer J

Mineralocorticoid Receptor in Endothelial Cells Contributes to Vascular Endothelial Growth Factor Receptor Inhibitor-Induced Vascular and Kidney Damage.

内皮细胞中的盐皮质激素受体导致血管内皮生长因子受体抑制剂引起的血管和肾脏损伤

Camarda Nicholas D, Lu Qing, Tesfu Angelina F, Liu Rui R, Ibarrola Jaime, Jaffe Iris Z

Effect of the Vascular Endothelial Growth Factor Inhibitor Toceranib on Cardiac Function and Endothelial Dysfunction Biomarkers in Dogs With Cancer.

血管内皮生长因子抑制剂托西拉尼对患癌犬心脏功能和内皮功能障碍生物标志物的影响

Lopez Katherine E, Meola Dawn M, Camarda Nicholas D, Upshaw Jenica N, Jaffe Iris Z, London Cheryl A, Yang Vicky K

Permissive Cardiotoxicity and Determination of Anthracycline Risk With Previous Anthracycline Exposure

允许性心脏毒性及既往蒽环类药物暴露风险的确定

Travers, Richard J; Camarda, Nicholas; Jaffe, Iris Z; Lizcano, Raphael A; Upshaw, Jenica N

Ponatinib, But Not the New Abl-Kinase Inhibitor Asciminib, Activates Platelets, Leukocytes, and Endothelial Cell TNF Signaling to Induce Atherosclerotic Plaque Inflammation, Myocardial Infarction, and Stroke

帕纳替尼(Ponatinib),而非新型Abl激酶抑制剂阿西米尼(Asciminib),可激活血小板、白细胞和内皮细胞的TNF信号通路,从而诱发动脉粥样硬化斑块炎症、心肌梗死和中风。

Stepanian, Alec; Travers, Richard J; Tesfu, Angelina; Wolter, Nicole L; Man, Joshua J; Lu, Qing; Shamsuzzaman, Sohel; Deaton, Rebecca A; Owens, Gary K; Chen, Christopher S; Jaffe, Iris Z