日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Safety, efficacy, and pharmacokinetics of gremubamab (MEDI3902), an anti-Pseudomonas aeruginosa bispecific human monoclonal antibody, in P. aeruginosa-colonised, mechanically ventilated intensive care unit patients: a randomised controlled trial

在定植铜绿假单胞菌的机械通气重症监护病房患者中,格瑞木单抗(MEDI3902,一种抗铜绿假单胞菌双特异性人源单克隆抗体)的安全性、有效性和药代动力学:一项随机对照试验

Chastre, Jean; François, Bruno; Bourgeois, Marc; Komnos, Apostolos; Ferrer, Ricard; Rahav, Galia; De Schryver, Nicolas; Lepape, Alain; Koksal, Iftihar; Luyt, Charles-Edouard; Sánchez-García, Miguel; Torres, Antoni; Eggimann, Philippe; Koulenti, Despoina; Holland, Thomas L; Ali, Omar; Shoemaker, Kathryn; Ren, Pin; Sauser, Julien; Ruzin, Alexey; Tabor, David E; Akhgar, Ahmad; Wu, Yuling; Jiang, Yu; DiGiandomenico, Antonio; Colbert, Susan; Vandamme, Drieke; Coenjaerts, Frank; Malhotra-Kumar, Surbhi; Timbermont, Leen; Oliver, Antonio; Barraud, Olivier; Bellamy, Terramika; Bonten, Marc; Goossens, Herman; Reisner, Colin; Esser, Mark T; Jafri, Hasan S

Performance of the Cepheid Methicillin-Resistant Staphylococcus aureus/S. aureus Skin and Soft Tissue Infection PCR Assay on Respiratory Samples from Mechanically Ventilated Patients for S. aureus Screening during the Phase 2 Double-Blind SAATELLITE Study

在 2 期双盲 SAATELLITE 研究中,对机械通气患者呼吸道样本进行金黄色葡萄球菌筛查时,Cepheid 耐甲氧西林金黄色葡萄球菌/金黄色葡萄球菌皮肤和软组织感染 PCR 检测的性能

Ruzin, Alexey; Barraud, Olivier; Yu, Li; François, Bruno; Sánchez-Garcia, Miguel; Eggimann, Philippe; Dequin, Pierre-François; Laterre, Pierre-François; Huberlant, Vincent; Viña, Lucia; Boulain, Thierry; Bretonniere, Cedric; Pugin, Jérôme; Trenado, José; Hernandez Padilla, Ana Catalina; Vignaud, Julie; Vandamme, Drieke; Goossens, Herman; Lammens, Christine; Ali, S Omar; Shoemaker, Kathryn; Ren, Pin; Colbert, Susan; Bellamy, Terramika; Sellman, Bret R; McCarthy, Michael; Jafri, Hasan S; Esser, Mark T

Characterisation of anti-alpha toxin antibody levels and colonisation status after administration of an investigational human monoclonal antibody, MEDI4893, against Staphylococcus aureus alpha toxin

对施用抗金黄色葡萄球菌α毒素的在研人源单克隆抗体MEDI4893后,抗α毒素抗体水平和定植状态进行表征

Ruzin, Alexey; Wu, Yuling; Yu, Li; Yu, Xiang-Qing; Tabor, David E; Mok, Hoyin; Tkaczyk, Christine; Jensen, Kathryn; Bellamy, Terramika; Roskos, Lorin; Esser, Mark T; Jafri, Hasan S

Risk prediction for Staphylococcus aureus surgical site infection following cardiothoracic surgery; A secondary analysis of the V710-P003 trial

预测心胸外科手术后金黄色葡萄球菌手术部位感染的风险;V710-P003试验的二次分析

Paling, Fleur P; Olsen, Karina; Ohneberg, Kristin; Wolkewitz, Martin; Fowler, Vance G Jr; DiNubile, Mark J; Jafri, Hasan S; Sifakis, Frangiscos; Bonten, Marc J M; Harbarth, Stephan J; Kluytmans, Jan A J W

Perceived barriers to pediatrician and family practitioner participation in pediatric clinical trials: Findings from the Clinical Trials Transformation Initiative

儿科医生和家庭医生参与儿科临床试验的感知障碍:临床试验转型计划的研究结果

Greenberg, Rachel G; Corneli, Amy; Bradley, John; Farley, John; Jafri, Hasan S; Lin, Li; Nambiar, Sumathi; Noel, Gary J; Wheeler, Chris; Tiernan, Rosemary; Smith, P Brian; Roberts, Jamie; Benjamin, Daniel K Jr

Parents' perceived obstacles to pediatric clinical trial participation: Findings from the clinical trials transformation initiative

家长对儿童临床试验参与障碍的认知:临床试验转型计划的调查结果

Greenberg, Rachel G; Gamel, Breck; Bloom, Diane; Bradley, John; Jafri, Hasan S; Hinton, Denise; Nambiar, Sumathi; Wheeler, Chris; Tiernan, Rosemary; Smith, P Brian; Roberts, Jamie; Benjamin, Daniel K Jr

Safety, Tolerability, and Pharmacokinetics of MEDI4893, an Investigational, Extended-Half-Life, Anti-Staphylococcus aureus Alpha-Toxin Human Monoclonal Antibody, in Healthy Adults

在健康成人中,MEDI4893(一种在研的、长半衰期的抗金黄色葡萄球菌α-毒素人单克隆抗体)的安全性、耐受性和药代动力学研究

Yu, Xiang-Qing; Robbie, Gabriel J; Wu, Yuling; Esser, Mark T; Jensen, Kathryn; Schwartz, Howard I; Bellamy, Terramika; Hernandez-Illas, Martha; Jafri, Hasan S

Characterization of alpha-toxin hla gene variants, alpha-toxin expression levels, and levels of antibody to alpha-toxin in hemodialysis and postsurgical patients with Staphylococcus aureus bacteremia

对血液透析和术后金黄色葡萄球菌菌血症患者的α-毒素HLA基因变异、α-毒素表达水平和抗α-毒素抗体水平进行表征

Sharma-Kuinkel, Batu K; Wu, Yuling; Tabor, David E; Mok, Hoyin; Sellman, Bret R; Jenkins, Amy; Yu, Li; Jafri, Hasan S; Rude, Thomas H; Ruffin, Felicia; Schell, Wiley A; Park, Lawrence P; Yan, Qin; Thaden, Joshua T; Messina, Julia A; Fowler, Vance G Jr; Esser, Mark T

Randomized, Double-Blind Study of the Safety of the Liquid Versus Lyophilized Formulation of Palivizumab in Premature Infants and Children with Chronic Lung Disease of Prematurity

一项随机、双盲研究,比较帕利珠单抗液体制剂与冻干制剂在早产儿慢性肺病患者中的安全性

Makari, Doris; Jensen, Kathryn M; Harris, Brian; Jafri, Hasan S

Randomized, Double-Blind Study of the Pharmacokinetics and Safety of Palivizumab Liquid Formulation Compared with Lyophilized Formulation

帕利珠单抗液体制剂与冻干制剂药代动力学和安全性比较的随机、双盲研究

Robbie, Gabriel J; Makari, Doris; Harris, Brian; Losonsky, Genevieve A; Jafri, Hasan S