日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

TDP-43 Aggregate Seeding Impairs Autoregulation and Causes TDP-43 Dysfunction

TDP-43 聚集接种会损害自身调节并导致 TDP-43 功能障碍

Lohany Dias Mamede, Miwei Hu, Amanda R Titus, Jaime Vaquer-Alicea, Rachel L French, Marc I Diamond, Timothy M Miller, Yuna M Ayala

FTD-tau S320F mutation stabilizes local structure and allosterically promotes amyloid motif-dependent aggregation

FTD-tau S320F突变可稳定局部结构,并通过变构作用促进淀粉样蛋白基序依赖性聚集。

Dailu Chen #,Sofia Bali #,Ruhar Singh,Aleksandra Wosztyl,Vishruth Mullapudi,Jaime Vaquer-Alicea,Parvathy Jayan,Shamiram Melhem,Harro Seelaar,John C van Swieten,Marc I Diamond,Lukasz A Joachimiak

Network of hotspot interactions cluster tau amyloid folds

热点相互作用网络聚集 tau 淀粉样褶皱

Vishruth Mullapudi #, Jaime Vaquer-Alicea #, Vaibhav Bommareddy, Anthony R Vega, Bryan D Ryder, Charles L White 3rd, Marc I Diamond, Lukasz A Joachimiak

VCP suppresses proteopathic seeding in neurons

VCP 抑制神经元中的蛋白质病播种

Jiang Zhu, Sara Pittman, Dhruva Dhavale, Rachel French, Jessica N Patterson, Mohamed Salman Kaleelurrrahuman, Yuanzi Sun, Jaime Vaquer-Alicea, Gianna Maggiore, Christoph S Clemen, William J Buscher, Jan Bieschke, Paul Kotzbauer, Yuna Ayala, Marc I Diamond, Albert A Davis, Conrad Weihl

Regulatory inter-domain interactions influence Hsp70 recruitment to the DnaJB8 chaperone

调控域间相互作用影响 Hsp70 向 DnaJB8 分子伴侣的募集

Bryan D Ryder ,Irina Matlahov ,Sofia Bali ,Jaime Vaquer-Alicea ,Patrick C A van der Wel ,Lukasz A Joachimiak

Ultrasensitive tau biosensor cells detect no seeding in Alzheimer's disease CSF

超灵敏的tau蛋白生物传感器细胞在阿尔茨海默病脑脊液中检测不到tau蛋白的播散。

Brian D Hitt ,Jaime Vaquer-Alicea ,Victor A Manon ,Joshua D Beaver ,Omar M Kashmer ,Jan N Garcia ,Marc I Diamond

Specific glycosaminoglycan chain length and sulfation patterns are required for cell uptake of tau versus α-synuclein and β-amyloid aggregates

细胞摄取 tau 与 α-突触核蛋白和 β-淀粉样蛋白聚集体需要特定的糖胺聚糖链长度和硫酸化模式

Barbara E Stopschinski, Brandon B Holmes, Gregory M Miller, Victor A Manon, Jaime Vaquer-Alicea, William L Prueitt, Linda C Hsieh-Wilson, Marc I Diamond

Novel autoimmune response in a tauopathy mouse model

tau 蛋白病小鼠模型中的新型自身免疫反应

Carlos J Nogueras-Ortiz, Hector J De Jesús-Cortes, Jaime Vaquer-Alicea, Irving E Vega

EFhd2 is a novel amyloid protein associated with pathological tau in Alzheimer's disease

EFhd2 是一种新型淀粉样蛋白,与阿尔茨海默病中的病理性 tau 有关

Yancy Ferrer-Acosta, Eva N Rodríguez-Cruz, François Orange, Hector De Jesús-Cortés, Bismark Madera, Jaime Vaquer-Alicea, Juan Ballester, Maxime J-F Guinel, George S Bloom, Irving E Vega