日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

AMPK activation is sufficient to increase skeletal muscle glucose uptake and glycogen synthesis but is not required for contraction-mediated increases in glucose metabolism

AMPK 激活足以增加骨骼肌葡萄糖摄取和糖原合成,但对于收缩介导的葡萄糖代谢增加并非必需

Ryan M Esquejo, Bina Albuquerque, Anna Sher, Matthew Blatnik, Kyle Wald, Matthew Peloquin, Jake Delmore, Erick Kindt, Wenlin Li, Jamey D Young, Kim Cameron, Russell A Miller

Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical Models

PF-06409577激活肝脏AMPK可纠正啮齿动物和灵长类动物临床前模型中的非酒精性脂肪性肝病并降低胆固醇

Ryan M Esquejo ,Christopher T Salatto ,Jake Delmore ,Bina Albuquerque ,Allan Reyes ,Yuji Shi ,Rob Moccia ,Emily Cokorinos ,Matthew Peloquin ,Mara Monetti ,Jason Barricklow ,Eliza Bollinger ,Brennan K Smith ,Emily A Day ,Chuong Nguyen ,Kieran F Geoghegan ,John M Kreeger ,Alan Opsahl ,Jessica Ward ,Amit S Kalgutkar ,David Tess ,Lynne Butler ,Norimitsu Shirai ,Timothy F Osborne ,Gregory R Steinberg ,Morris J Birnbaum ,Kimberly O Cameron ,Russell A Miller

Activation of Skeletal Muscle AMPK Promotes Glucose Disposal and Glucose Lowering in Non-human Primates and Mice

骨骼肌 AMPK 的激活促进非人类灵长类动物和小鼠的葡萄糖处理和血糖降低

Emily C Cokorinos, Jake Delmore, Allan R Reyes, Bina Albuquerque, Rasmus Kjøbsted, Nicolas O Jørgensen, Jean-Luc Tran, Aditi Jatkar, Katherine Cialdea, Ryan M Esquejo, John Meissen, Matthew F Calabrese, Jason Cordes, Robert Moccia, David Tess, Christopher T Salatto, Timothy M Coskran, Alan C Opsahl,

The interaction of bortezomib with multidrug transporters: implications for therapeutic applications in advanced multiple myeloma and other neoplasias

硼替佐米与多药转运蛋白的相互作用:对晚期多发性骨髓瘤和其他肿瘤治疗应用的影响

Robert O'Connor, Melissa G Ooi, Justine Meiller, Jana Jakubikova, Steffen Klippel, Jake Delmore, Paul Richardson, Kenneth Anderson, Martin Clynes, Constantine S Mitsiades, Peter O'Gorman

Methyljasmonate displays in vitro and in vivo activity against multiple myeloma cells

甲基茉莉酸酯在体外和体内均表现出对抗多发性骨髓瘤细胞的活性

Steffen Klippel, Jana Jakubikova, Jake Delmore, Melissa Ooi, Douglas McMillin, Efstathios Kastritis, Jacob Laubach, Paul G Richardson, Kenneth C Anderson, Constantine S Mitsiades