日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Naphthoquinone-derived tridentate Ru(II) and Os(II) organometallics with exceptional cytotoxicity: synthesis, characterization, stability in aqueous solution and biological in vitro evaluation

萘醌衍生的三齿Ru(II)和Os(II)有机金属化合物具有优异的细胞毒性：合成、表征、水溶液稳定性及体外生物学评价

期刊:Dalton Transactions
影响因子:3.3
doi:10.1039/d5dt01649e
Rosner, Alexander; Geisler, Heiko; Hejl, Michaela; Gradl, Mathias; Legin, Anton A; Prado-Roller, Alexander; Jakupec, Michael A; Heffeter, Petra; Berger, Walter; Keppler, Bernhard K; Kandioller, Wolfgang
细胞生物学
毒理研究
发表日期：2026
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Selectivity for TP53 signalling drives the mode of action of a highly potent N,O,O-tridentate naphthoquinone-based organo-ruthenium anticancer drug candidate

一种高效的基于N,O,O-三齿萘醌的有机钌抗癌候选药物的作用机制取决于其对TP53信号通路的选择性。

期刊:Chemical Science
影响因子:7.4
doi:10.1039/d5sc00735f
Rosner, Alexander; Skos, Lukas; Mendrina, Theresa; Baier, Dina; Hejl, Michaela; Borutzki, Yasmin; Gradl, Mathias; Geisler, Heiko; Mohr, Thomas; Legin, Anton; Jakupec, Michael A; Bileck, Andrea; Gerner, Christopher; Koellensperger, Gunda; Heffeter, Petra; Berger, Walter; Keppler, Bernhard K; Kandioller, Wolfgang; Meier-Menches, Samuel M
信号转导
肿瘤
P53
肿瘤免疫
发表日期：2025
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First In Vitro Characterization of Salinomycinic Acid-Containing Two-Line Ferrihydrite Composites with Pronounced Antitumor Activity as MRI Contrast Agents.

首次对具有显著抗肿瘤活性的含盐霉素酸的双线水铁矿复合材料进行体外表征，作为 MRI 造影剂

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26178405
Pashkunova-Martic Irena, Friske Joachim, Paneva Daniela, Cherkezova-Zheleva Zara, Hejl Michaela, Jakupec Michael, Braeuer Simone, Dorkov Peter, Keppler Bernhard K, Helbich Thomas H, Ivanova Juliana
肿瘤
发表日期：2025
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Exploring the Anticancer Properties of 4-Phenylthiazole-Based Ru(II) and Os(II) Metallacycles Featuring 1-Methylimidazole as N-Donor Functionality

探索以1-甲基咪唑为N-供体官能团的4-苯基噻唑基Ru(II)和Os(II)金属环的抗癌特性

期刊:Bioinorganic Chemistry and Applications
影响因子:4.1
doi:10.1155/bca/6352081
Getreuer, Paul; Mendrina, Theresa; van Terwingen, Steven; Marretta, Laura; Dömötör, Orsolya; Wenisch, Dominik; Hejl, Michaela; Heffeter, Petra; Berger, Walter; Jakupec, Michael A; Terenzi, Alessio; Keppler, Bernhard K; Kandioller, Wolfgang
肿瘤
肿瘤免疫
发表日期：2025
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A Comparative Study on the Complexation of the Anticancer Iron Chelator VLX600 with Essential Metal Ions

抗癌铁螯合剂VLX600与人体必需金属离子络合作用的比较研究

期刊:Inorganic Chemistry
影响因子:4.3
doi:10.1021/acs.inorgchem.3c03259
Vivien Pósa, Anja Federa, Klaudia Cseh, Dominik Wenisch, Gabriella Spengler, Nóra V May, Norbert Lihi, Gergely F Samu, Michael A Jakupec, Bernhard K Keppler, Christian R Kowol, Éva A Enyedy
肿瘤
发表日期：2024
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Platinum(IV)-Loaded Degraded Glycol Chitosan as Efficient Platinum(IV) Drug Delivery Platform

负载铂(IV)的降解乙二醇壳聚糖作为高效的铂(IV)药物递送平台

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics15041050
Lerchbammer-Kreith, Yvonne; Sommerfeld, Nadine S; Cseh, Klaudia; Weng-Jiang, Xian; Odunze, Uchechukwu; Schätzlein, Andreas G; Uchegbu, Ijeoma F; Galanski, Mathea S; Jakupec, Michael A; Keppler, Bernhard K
发表日期：2023
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Combination of Drug Delivery Properties of PAMAM Dendrimers and Cytotoxicity of Platinum(IV) Complexes-A More Selective Anticancer Treatment?

PAMAM树枝状聚合物的药物输送特性与铂（IV）配合物的细胞毒性的结合——一种更具选择性的抗癌治疗方法？

期刊:Pharmaceutics
影响因子:4.9
doi:10.3390/pharmaceutics15051515
Yvonne Lerchbammer-Kreith, Michaela Hejl, Petra Vician, Michael A Jakupec, Walter Berger, Mathea S Galanski, Bernhard K Keppler
肿瘤
其它细胞
发表日期：2023
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Anticancer Tungstenocenes with a Diverse Set of (O,O-), (O, S-) and (O, N-) Chelates-A Detailed Biological Study Using an Improved Evaluation via 3D Spheroid Models

具有多种 (O,O-)、(O, S-) 和 (O, N-) 螯合物的抗癌钨二茂物 - 使用通过 3D 球体模型改进的评估方法进行的详细生物学研究

期刊:Pharmaceutics
影响因子:4.9
doi:10.3390/pharmaceutics15071875
Klaudia Cseh, Iker Berasaluce, Valentin Fuchs, Alexandra Banc, Andreas Schweikert, Alexander Prado-Roller, Michaela Hejl, Debora Wernitznig, Gunda Koellensperger, Michael A Jakupec, Wolfgang Kandioller, Michael S Malarek, Bernhard K Keppler
肿瘤
发表日期：2023
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Quaternary Ammonium Palmitoyl Glycol Chitosan (GCPQ) Loaded with Platinum-Based Anticancer Agents-A Novel Polymer Formulation for Anticancer Therapy

载有铂基抗癌剂的季铵盐棕榈酰乙二醇壳聚糖 (GCPQ)——一种用于抗癌治疗的新型聚合物制剂

期刊:Pharmaceuticals
影响因子:
doi:10.3390/ph16071027
Yvonne Lerchbammer-Kreith, Michaela Hejl, Nadine S Sommerfeld, Xian Weng-Jiang, Uchechukwu Odunze, Ryan D Mellor, David G Workman, Michael A Jakupec, Andreas G Schätzlein, Ijeoma F Uchegbu, Mathea S Galanski, Bernhard K Keppler
肿瘤
发表日期：2023
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Novel Salinomycin-Based Paramagnetic Complexes-First Evaluation of Their Potential Theranostic Properties

新型盐霉素基顺磁性配合物——其潜在诊疗性能的初步评估

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics14112319
Pashkunova-Martic, Irena; Kukeva, Rositsa; Stoyanova, Radostina; Pantcheva, Ivayla; Dorkov, Peter; Friske, Joachim; Hejl, Michaela; Jakupec, Michael; Hohagen, Mariam; Legin, Anton; Lubitz, Werner; Keppler, Bernhard K; Helbich, Thomas H; Ivanova, Juliana
发表日期：2022
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