日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Comprehensive evaluation of human-derived anti-poly-GA antibodies in cellular and animal models of C9orf72 disease

在C9orf72疾病的细胞和动物模型中对人源抗poly-GA抗体进行全面评估

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2123487119
Jambeau, Melanie; Meyer, Kevin D; Hruska-Plochan, Marian; Tabet, Ricardos; Lee, Chao-Zong; Ray-Soni, Ananya; Aguilar, Corey; Savage, Kitty; Mishra, Nibha; Cavegn, Nicole; Borter, Petra; Lin, Chun-Chia; Jansen-West, Karen R; Jiang, Jie; Freyermuth, Fernande; Li, Nan; De Rossi, Pierre; Pérez-Berlanga, Manuela; Jiang, Xin; Daughrity, Lilian M; Pereira, João; Narayanan, Sarav; Gu, Yuanzheng; Dhokai, Shekhar; Dalkilic-Liddle, Isin; Maniecka, Zuzanna; Weber, Julien; Workman, Michael; McAlonis-Downes, Melissa; Berezovski, Eugene; Zhang, Yong-Jie; Berry, James; Wainger, Brian J; Kankel, Mark W; Rushe, Mia; Hock, Christoph; Nitsch, Roger M; Cleveland, Don W; Petrucelli, Leonard; Gendron, Tania F; Montrasio, Fabio; Grimm, Jan; Polymenidou, Magdalini; Lagier-Tourenne, Clotilde
细胞生物学
发表日期：2022
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ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS

FUS 中的 ALS/FTD 关联突变可抑制轴突内蛋白质合成并引发疾病，但 FUS 不会丧失核功能

期刊:Neuron
影响因子:14.7
doi:10.1016/j.neuron.2020.04.006
Jone López-Erauskin, Takahiro Tadokoro, Michael W Baughn, Brian Myers, Melissa McAlonis-Downes, Carlos Chillon-Marinas, Joshua N Asiaban, Jonathan Artates, Anh T Bui, Anne P Vetto, Sandra K Lee, Ai Vy Le, Ying Sun, Mélanie Jambeau, Jihane Boubaker, Deborah Swing, Jinsong Qiu, Geoffrey G Hicks, Zheng
信号转导
发表日期：2020
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ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS

FUS 中的 ALS/FTD 关联突变可抑制轴突内蛋白质合成并引发疾病，但 FUS 不会丧失核功能

期刊:Neuron
影响因子:14.7
doi:10.1016/j.neuron.2018.09.044
Jone López-Erauskin, Takahiro Tadokoro, Michael W Baughn, Brian Myers, Melissa McAlonis-Downes, Carlos Chillon-Marinas, Joshua N Asiaban, Jonathan Artates, Anh T Bui, Anne P Vetto, Sandra K Lee, Ai Vy Le, Ying Sun, Mélanie Jambeau, Jihane Boubaker, Deborah Swing, Jinsong Qiu, Geoffrey G Hicks, Zheng
信号转导
IHC
IP
WB
FUS
发表日期：2018
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CUG initiation and frameshifting enable production of dipeptide repeat proteins from ALS/FTD C9ORF72 transcripts

CUG 启动和移码使 ALS/FTD C9ORF72 转录本能够产生二肽重复蛋白

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-017-02643-5
Ricardos Tabet, Laure Schaeffer, Fernande Freyermuth, Melanie Jambeau, Michael Workman, Chao-Zong Lee, Chun-Chia Lin, Jie Jiang, Karen Jansen-West, Hussein Abou-Hamdan, Laurent Désaubry, Tania Gendron, Leonard Petrucelli, Franck Martin, Clotilde Lagier-Tourenne
信号转导
发表日期：2018
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Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation

ALS相关蛋白TDP-43的功能性和动态聚合作用可拮抗其病理性聚集。

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-017-00062-0
Tariq Afroz ,Eva-Maria Hock ,Patrick Ernst ,Chiara Foglieni ,Melanie Jambeau ,Larissa A B Gilhespy ,Florent Laferriere ,Zuzanna Maniecka ,Andreas Plückthun ,Peer Mittl ,Paolo Paganetti ,Frédéric H T Allain ,Magdalini Polymenidou
ALS
发表日期：2017
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Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss

突变 FUS 蛋白的毒性功能获得对于触发细胞自主运动神经元丢失至关重要

期刊:EMBO Journal
影响因子:9.4
doi:10.15252/embj.201592559
Jelena Scekic-Zahirovic, Oliver Sendscheid, Hajer El Oussini, Mélanie Jambeau, Ying Sun, Sina Mersmann, Marina Wagner, Stéphane Dieterlé, Jérome Sinniger, Sylvie Dirrig-Grosch, Kevin Drenner, Marie-Christine Birling, Jinsong Qiu, Yu Zhou, Hairi Li, Xiang-Dong Fu, Caroline Rouaux, Tatyana Shelkovniko
神经
其它细胞
ELISA
WB
Donkey
IgG
发表日期：2016
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