日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cockayne Syndrome Patient iPSC-Derived Brain Organoids and Neurospheres Show Early Transcriptional Dysregulation of Biological Processes Associated with Brain Development and Metabolism

科凯恩综合征患者 iPSC 衍生的脑类器官和神经球显示与脑发育和代谢相关的生物过程的早期转录失调

Leon-Phillip Szepanowski, Wasco Wruck, Julia Kapr, Andrea Rossi, Ellen Fritsche, Jean Krutmann, James Adjaye

Forskolin induces FXR expression and enhances maturation of iPSC-derived hepatocyte-like cells

福斯可林诱导 FXR 表达并促进 iPSC 衍生的肝细胞样细胞的成熟

Christiane Loerch, Leon-Phillip Szepanowski, Julian Reiss, James Adjaye, Nina Graffmann

Hemozoin induces malaria via activation of DNA damage, p38 MAPK and neurodegenerative pathways in a human iPSC-derived neuronal model of cerebral malaria

在人类 iPSC 衍生的脑疟神经元模型中,疟色素通过激活 DNA 损伤、p38 MAPK 和神经退行性通路诱发疟疾

Abida Islam Pranty #, Leon-Phillip Szepanowski #, Wasco Wruck, Akua Afriyie Karikari, James Adjaye

JNK Signalling Regulates Self-Renewal of Proliferative Urine-Derived Renal Progenitor Cells via Inhibition of Ferroptosis

JNK 信号通过抑制铁死亡来调节增殖性尿源性肾祖细胞的自我更新

Lisa Nguyen, Leonie Thewes, Michelle Westerhoff, Wasco Wruck, Andreas S Reichert, Carsten Berndt, James Adjaye

Derivation of the Immortalized Cell Line UM51-PrePodo-hTERT and Its Responsiveness to Angiotensin II and Activation of the RAAS Pathway

永生化细胞系 UM51-PrePodo-hTERT 的衍生及其对血管紧张素 II 和 RAAS 通路激活的反应性

Lars Erichsen, Lea Doris Friedel Kloss, Chantelle Thimm, Martina Bohndorf, Kira Schichel, Wasco Wruck, James Adjaye

Free Bilirubin Induces Neuro-Inflammation in an Induced Pluripotent Stem Cell-Derived Cortical Organoid Model of Crigler-Najjar Syndrome

游离胆红素在诱导性多能干细胞衍生的 Crigler-Najjar 综合征皮质类器官模型中诱发神经炎症

Abida Islam Pranty, Wasco Wruck, James Adjaye

Unveiling Angiotensin II and Losartan-Induced Gene Regulatory Networks Using Human Urine-Derived Podocytes

利用人类尿液来源的足细胞揭示血管紧张素 II 和氯沙坦诱导的基因调控网络

Chantelle Thimm, Lars Erichsen, Wasco Wruck, James Adjaye

Secreted Cytokines within the Urine of AKI Patients Modulate TP53 and SIRT1 Levels in a Human Podocyte Cell Model

AKI 患者尿液中分泌的细胞因子调节人类足细胞模型中的 TP53 和 SIRT1 水平

Lars Erichsen, Chantelle Thimm, Wasco Wruck, Daniela Kaierle, Manon Schless, Laura Huthmann, Thomas Dimski, Detlef Kindgen-Milles, Timo Brandenburger, James Adjaye

Sensitivity of Human Induced Pluripotent Stem Cells and Thereof Differentiated Kidney Proximal Tubular Cells towards Selected Nephrotoxins

人类诱导性多能干细胞及其分化的肾近端小管细胞对特定肾毒素的敏感性

Isaac Musong Mboni-Johnston, Nazih Mohamed Zakari Kouidrat, Cornelia Hirsch, Andreas Georg Weber, Alexander Meißner, James Adjaye, Nicole Schupp

Activation of the Renin-Angiotensin System Disrupts the Cytoskeletal Architecture of Human Urine-Derived Podocytes

肾素-血管紧张素系统的激活会破坏人类尿液衍生足细胞的细胞骨架结构

Lars Erichsen, Chantelle Thimm, Martina Bohndorf, Md Shaifur Rahman, Wasco Wruck, James Adjaye