Global hypo-methylation in a proportion of glioblastoma enriched for an astrocytic signature is associated with increased invasion and altered immune landscape
在富含星形胶质细胞特征的胶质母细胞瘤中,部分肿瘤细胞的低甲基化与侵袭性增强和免疫微环境改变相关。
期刊:Elife
影响因子:6.4
doi:10.7554/eLife.77335
James Boot ,Gabriel Rosser ,Dailya Kancheva ,Claire Vinel ,Yau Mun Lim ,Nicola Pomella ,Xinyu Zhang ,Loredana Guglielmi ,Denise Sheer ,Michael Barnes ,Sebastian Brandner ,Sven Nelander ,Kiavash Movahedi ,Silvia Marino
免疫/内分泌
肿瘤免疫
肿瘤细胞
表观遗传
细胞生物学
胶质细胞
肿瘤