PD-1 and TIGIT blockade differentially affect tumour cell survival under hypoxia and glucose deprived conditions in oesophageal adenocarcinoma; implications for overcoming resistance to PD-1 blockade in hypoxic tumours
PD-1 和 TIGIT 阻断对食管腺癌在缺氧和缺糖条件下肿瘤细胞存活率有不同的影响；对克服缺氧肿瘤对 PD-1 阻断的耐药性具有重要意义
期刊:Translational Oncology
影响因子:4.5
doi:10.1016/j.tranon.2022.101381
Maria Davern, Marie-Claire Fitzgerald, Croí E Buckley, Aisling B Heeran, Noel E Donlon, Jason McGrath, Fiona O' Connell, Malvika R Deshpande, Conall Hayes, Jamie MacDonald, Andrew D Sheppard, John V Reynolds, Stephen G Maher, Niamh Lynam-Lennon, Brona Murphy, Joanne Lysaght
