日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeted nutritional intervention attenuates experimental lung cancer cachexia

有针对性的营养干预可减轻实验性肺癌恶病质

Wouter R P H van de Worp, Jan Theys, Cecile J A Wolfs, Frank Verhaegen, Annemie M W J Schols, Ardy van Helvoort, Ramon C J Langen

Multiplex genetic manipulations in Clostridium butyricum and Clostridium sporogenes to secrete recombinant antigen proteins for oral-spore vaccination

对丁酸梭菌和产孢梭菌进行多重基因操作以分泌重组抗原蛋白用于口服孢子疫苗接种

Yanchao Zhang, Tom S Bailey, Philip Hittmeyer, Ludwig J Dubois, Jan Theys, Philippe Lambin

Development of a CRISPR-Cas12a system for efficient genome engineering in clostridia

开发 CRISPR-Cas12a 系统用于梭菌的高效基因组工程

Yanchao Zhang, Aleksandra M Kubiak, Tom S Bailey, Luuk Claessen, Philip Hittmeyer, Ludwig Dubois, Jan Theys, Philippe Lambin

Heterologous Gene Regulation in Clostridia: Rationally Designed Gene Regulation for Industrial and Medical Applications

梭菌中的异源基因调控:合理设计的基因调控用于工业和医学应用

Yanchao Zhang, Tom S Bailey, Aleksandra M Kubiak, Philippe Lambin, Jan Theys

Inhibition of Extracellular Cathepsin D Reduces Hepatic Lipid Accumulation and Leads to Mild Changes in Inflammationin NASH Mice

抑制细胞外组织蛋白酶 D 可减少 NASH 小鼠肝脏脂质蓄积并导致炎症轻微变化

Tulasi Yadati, Tom Houben, Albert Bitorina, Yvonne Oligschlaeger, Marion J Gijbels, Ronny Mohren, Dieter Lütjohann, Princy Khurana, Sandeep Goyal, Aditya Kulkarni, Jan Theys, Berta Cillero-Pastor, Ronit Shiri-Sverdlov

Efficient Secretion of Murine IL-2 From an Attenuated Strain of Clostridium sporogenes, a Novel Delivery Vehicle for Cancer Immunotherapy

产孢梭菌减毒菌株有效分泌小鼠 IL-2,这是一种用于癌症免疫治疗的新型运载载体

Aleksandra M Kubiak, Tom S Bailey, Ludwig J Dubois, Jan Theys, Philippe Lambin

Sex-opposed inflammatory effects of 27-hydroxycholesterol are mediated via differences in estrogen signaling

27-羟基胆固醇的性别差异性炎症作用是通过雌激素信号传导的差异介导的。

Tom Houben ,Albert V Bitorina ,Yvonne Oligschlaeger ,Mike Lj Jeurissen ,Sander Rensen ,S Eleonore Köhler ,Marit Westerterp ,Dieter Lütjohann ,Jan Theys ,Andrea Romano ,Jogchum Plat ,Ronit Shiri-Sverdlov

EGFRvIII expression triggers a metabolic dependency and therapeutic vulnerability sensitive to autophagy inhibition

EGFRvIII 表达引发对自噬抑制敏感的代谢依赖性和治疗脆弱性

Barry Jutten, Tom G Keulers, Hanneke J M Peeters, Marco B E Schaaf, Kim G M Savelkouls, Inge Compter, Ruud Clarijs, Olaf E M G Schijns, Linda Ackermans, Onno P M Teernstra, Marijke I Zonneveld, Resi M E Colaris, Ludwig Dubois, Marc A Vooijs, Johan Bussink, Julio Sotelo, Jan Theys, Guido Lammering, K

Identification of MEK162 as a Radiosensitizer for the Treatment of Glioblastoma

鉴定 MEK162 作为治疗胶质母细胞瘤的放射增敏剂

Ravi S Narayan, Ana Gasol, Paul L G Slangen, Fleur M G Cornelissen, Tonny Lagerweij, Hou Y Y E Veldman, Rogier Dik, Jaap van den Berg, Ben J Slotman, Tom Würdinger, Daphne A Haas-Kogan, Lukas J A Stalpers, Brigitta G Baumert, Bart A Westerman #, Jan Theys #, Peter Sminia #

Myeloid DLL4 Does Not Contribute to the Pathogenesis of Non-Alcoholic Steatohepatitis in Ldlr-/- Mice

髓系 DLL4 不参与 Ldlr-/- 小鼠非酒精性脂肪性肝炎的发病机制

Mike L J Jeurissen, Sofie M A Walenbergh, Tom Houben, Tim Hendrikx, Jieyi Li, Yvonne Oligschlaeger, Patrick J van Gorp, Marion J J Gijbels, Albert Bitorina, Isabell Nessel, Freddy Radtke, Marc Vooijs, Jan Theys, Ronit Shiri-Sverdlov