文献库，生知库 | 链接生命科学的每一步

日期影响因子

Application of Fluorine- and Nitrogen-Walk Approaches: Defining the Structural and Functional Diversity of 2-Phenylindole Class of Cannabinoid 1 Receptor Positive Allosteric Modulators

氟和氮行走方法的应用：定义 2-苯基吲哚类大麻素 1 受体正变构调节剂的结构和功能多样性

期刊:Journal of Medicinal Chemistry

影响因子:6.8

doi:10.1021/acs.jmedchem.9b01142

Sumanta Garai, Pushkar M Kulkarni, Peter C Schaffer, Luciana M Leo, Asher L Brandt, Ayat Zagzoog, Tallan Black, Xiaoyan Lin, Dow P Hurst, David R Janero, Mary E Abood, Anaelle Zimmowitch, Alex Straiker, Roger G Pertwee, Melanie Kelly, Anna-Maria Szczesniak, Eileen M Denovan-Wright, Ken Mackie, Andre

发表日期：2020

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Functional selectivity at G-protein coupled receptors: Advancing cannabinoid receptors as drug targets

G蛋白偶联受体的功能选择性：推进大麻素受体作为药物靶点的研究

期刊:Biochemical Pharmacology

影响因子:5.6

doi:10.1016/j.bcp.2016.11.014

Mallipeddi, Srikrishnan; Janero, David R; Zvonok, Nikolai; Makriyannis, Alexandros

发表日期：2017

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Enantiospecific Allosteric Modulation of Cannabinoid 1 Receptor

大麻素1受体的对映体特异性变构调节

期刊:ACS Chemical Neuroscience

影响因子:3.9

doi:10.1021/acschemneuro.6b00310

Laprairie, Robert B; Kulkarni, Pushkar M; Deschamps, Jeffrey R; Kelly, Melanie E M; Janero, David R; Cascio, Maria G; Stevenson, Lesley A; Pertwee, Roger G; Kenakin, Terrence P; Denovan-Wright, Eileen M; Thakur, Ganesh A

发表日期：2017

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Leveraging allostery to improve G protein-coupled receptor (GPCR)-directed therapeutics: cannabinoid receptor 1 as discovery target

利用变构效应改善G蛋白偶联受体（GPCR）靶向治疗：以大麻素受体1为发现靶点

期刊:Expert Opinion on Drug Discovery

影响因子:4.9

doi:10.1080/17460441.2016.1245289

Janero, David R; Thakur, Ganesh A

GPCR/Calcium/cAMP

发表日期：2016

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Mapping Cannabinoid 1 Receptor Allosteric Site(s): Critical Molecular Determinant and Signaling Profile of GAT100, a Novel, Potent, and Irreversibly Binding Probe

绘制大麻素 1 受体变构位点：GAT100（一种新型、有效且不可逆结合的探针）的关键分子决定因素和信号传导概况

期刊:ACS Chemical Neuroscience

影响因子:4.1

doi:10.1021/acschemneuro.6b00041

Robert B Laprairie, Abhijit R Kulkarni, Pushkar M Kulkarni, Dow P Hurst, Diane Lynch, Patricia H Reggio, David R Janero, Roger G Pertwee, Lesley A Stevenson, Melanie E M Kelly, Eileen M Denovan-Wright, Ganesh A Thakur

发表日期：2016

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17β-estradiol (E2) in membranes: Orientation and dynamic properties

膜中的 17β-雌二醇 (E2)：取向和动态特性

影响因子:3.3

doi:10.1016/j.bbamem.2015.11.015

Jason J Guo, De-Ping Yang, Xiaoyu Tian, V Kiran Vemuri, Dali Yin, Chen Li, Richard I Duclos Jr, Lingling Shen, Xiaoyu Ma, David R Janero, Alexandros Makriyannis

发表日期：2016

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Therapeutic Efficacy of an ω-3-Fatty Acid-Containing 17-β Estradiol Nano-Delivery System against Experimental Atherosclerosis

含ω-3脂肪酸的17-β雌二醇纳米递送系统对实验性动脉粥样硬化的治疗作用

期刊:PLoS One

影响因子:2.9

doi:10.1371/journal.pone.0147337

Dipti Deshpande, Sravani Kethireddy, David R Janero, Mansoor M Amiji

动脉粥样硬化

发表日期：2016

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Molecular-interaction and signaling profiles of AM3677, a novel covalent agonist selective for the cannabinoid 1 receptor

AM3677 是一种新型的选择性大麻素 1 受体共价激动剂，本文研究了其分子相互作用和信号传导特性。

期刊:ACS Chemical Neuroscience

影响因子:4.1

doi:10.1021/acschemneuro.5b00090.

David R Janero ,Suma Yaddanapudi ,Nikolai Zvonok ,Kumar V Subramanian ,Vidyanand G Shukla ,Edward Stahl ,Lei Zhou ,Dow Hurst ,James Wager-Miller ,Laura M Bohn ,Patricia H Reggio ,Ken Mackie ,Alexandros Makriyannis

发表日期：2015

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Therapeutic modulation of cannabinoid lipid signaling: metabolic profiling of a novel antinociceptive cannabinoid-2 receptor agonist

大麻素脂质信号的治疗调节：新型抗伤害性大麻素-2 受体激动剂的代谢分析

期刊:Life Sciences

影响因子:5.2

doi:10.1016/j.lfs.2012.06.019

Jodianne T Wood, Dustin M Smith, David R Janero, Alexander M Zvonok, Alexandros Makriyannis

发表日期：2013

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Endocannabinoid enzyme engineering: soluble human thio-monoacylglycerol lipase (sol-S-hMGL)

内源性大麻素酶工程：可溶性人类硫代单酰甘油脂肪酶（sol-S-hMGL）

期刊:ACS Chemical Neuroscience

影响因子:4.1

doi:10.1021/cn3000263

Ioannis Karageorgos, Nikolai Zvonok, David R Janero, V Kiran Vemuri, Vidyanand Shukla, Thomas E Wales, John R Engen, Alexandros Makriyannis

发表日期：2012

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