日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

A long-term follow-up study of sotatercept for treatment of pulmonary arterial hypertension: interim results of SOTERIA

索他西普治疗肺动脉高压的长期随访研究：SOTERIA研究的中期结果

期刊:European Respiratory Journal
影响因子:21
doi:10.1183/13993003.01435-2024
Preston, Ioana R; Badesch, David; Ghofrani, Hossein-Ardeschir; Gibbs, J Simon R; Gomberg-Maitland, Mardi; Hoeper, Marius M; Humbert, Marc; McLaughlin, Vallerie V; Waxman, Aaron B; Manimaran, Solaiappan; Mikhailova, Elina; Reddy, Madhavi; Lau, Anna; de Oliveira Pena, Janethe; Souza, Rogerio
肺动脉高压
心血管
发表日期：2025
文献求助 收藏

Efficacy and safety of the activin signalling inhibitor, sotatercept, in a pooled analysis of PULSAR and STELLAR studies

PULSAR 和 STELLAR 研究的汇总分析显示，激活素信号抑制剂 sotatercept 具有疗效和安全性。

期刊:European Respiratory Journal
影响因子:21
doi:10.1183/13993003.01424-2024
Hoeper, Marius M; Gomberg-Maitland, Mardi; Badesch, David B; Gibbs, J Simon R; Grünig, Ekkehard; Kopeć, Grzegorz; McLaughlin, Vallerie V; Meyer, Gisela; Olsson, Karen M; Preston, Ioana R; Rosenkranz, Stephan; Souza, Rogerio; Waxman, Aaron B; Perchenet, Loïc; Strait, James; Xing, Aiwen; Manimaran, Solaiappan; Wang, Xuelong; Miller, Barry; Cornell, Alexandra G; de Oliveira Pena, Janethe; Ghofrani, H Ardeschir; Humbert, Marc
信号转导
发表日期：2025
文献求助 收藏

Population Pharmacokinetic/Pharmacodynamic and Exposure-Response Modeling Analyses of Sotatercept in Healthy Participants and Patients with Pulmonary Arterial Hypertension

索他西普在健康受试者和肺动脉高压患者中的群体药代动力学/药效学和暴露-反应模型分析

期刊:Clinical Pharmacology & Therapeutics
影响因子:5.5
doi:10.1002/cpt.3524
Ait-Oudhia, Sihem; Jaworowicz, David; Hu, Ziheng; Gaurav, Mitali; Barcomb, Heather; Hu, Shuai; Bihorel, Sébastien; Balasubrahmanyam, Budda; Mistry, Bipin; de Oliveira Pena, Janethe; Wenning, Larissa; Gheyas, Ferdous
肺动脉高压
心血管
发表日期：2025
文献求助 收藏

Long-Term Mortality and Morbidity Impact on Patients with Pulmonary Arterial Hypertension (PAH) If Access to Sotatercept Is Delayed: A Simulation Model

延迟使用索他西普对肺动脉高压（PAH）患者长期死亡率和发病率的影响：模拟模型

期刊:Advances in Therapy
影响因子:4
doi:10.1007/s12325-025-03241-4
Alsumali, Adnan; McLaughlin, Vallerie; Chevure, Jestinah; Klok, Rogier; Zhang, Wenjie; Martinez, Eliana C; Pausch, Christine; De Oliveira Pena, Janethe; van de Wetering, Gijs; Jootun, Murvin; Lautsch, Dominik; Hoeper, Marius M
肺动脉高压
心血管
发表日期：2025
文献求助 收藏

Population Health Model Predicting the Long-Term Impact of Sotatercept on Morbidity and Mortality in Patients with Pulmonary Arterial Hypertension (PAH)

人口健康模型预测索他西普对肺动脉高压（PAH）患者发病率和死亡率的长期影响

期刊:Advances in Therapy
影响因子:4
doi:10.1007/s12325-023-02684-x
McLaughlin, Vallerie; Alsumali, Adnan; Liu, Rongzhe; Klok, Rogier; Martinez, Eliana C; Nourhussein, Iman; Bernotas, David; Chevure, Jestinah; Pausch, Christine; De Oliveira Pena, Janethe; Lautsch, Dominik; Hoeper, Marius M
肺动脉高压
心血管
发表日期：2024
文献求助 收藏

Population pharmacokinetic modeling of sotatercept in healthy participants and patients with pulmonary arterial hypertension

在健康受试者和肺动脉高压患者中建立索他西普的群体药代动力学模型

期刊:Cpt-Pharmacometrics & Systems Pharmacology
影响因子:3
doi:10.1002/psp4.13166
Ait-Oudhia, Sihem; Jaworowicz, David; Hu, Ziheng; Bihorel, Sébastien; Hu, Shuai; Balasubrahmanyam, Budda; Mistry, Bipin; de Oliveira Pena, Janethe; Wenning, Larissa; Gheyas, Ferdous
肺动脉高压
心血管
发表日期：2024
文献求助 收藏

Sotatercept for the treatment of pulmonary arterial hypertension: PULSAR open-label extension

索他西普治疗肺动脉高压：PULSAR开放标签扩展研究

期刊:European Respiratory Journal
影响因子:21
doi:10.1183/13993003.01347-2022
Humbert, Marc; McLaughlin, Vallerie; Gibbs, J Simon R; Gomberg-Maitland, Mardi; Hoeper, Marius M; Preston, Ioana R; Souza, Rogerio; Waxman, Aaron B; Ghofrani, Hossein-Ardeschir; Escribano Subias, Pilar; Feldman, Jeremy; Meyer, Gisela; Montani, David; Olsson, Karen M; Manimaran, Solaiappan; de Oliveira Pena, Janethe; Badesch, David B
肺动脉高压
心血管
发表日期：2023
文献求助 收藏

Effects of sotatercept on haemodynamics and right heart function: analysis of the STELLAR trial

索他西普对血液动力学和右心功能的影响：STELLAR试验分析

期刊:European Respiratory Journal
影响因子:21
doi:10.1183/13993003.01107-2023
Souza, Rogerio; Badesch, David B; Ghofrani, H Ardeschir; Gibbs, J Simon R; Gomberg-Maitland, Mardi; McLaughlin, Vallerie V; Preston, Ioana R; Waxman, Aaron B; Grünig, Ekkehard; Kopeć, Grzegorz; Meyer, Gisela; Olsson, Karen M; Rosenkranz, Stephan; Lin, Jianxin; Johnson-Levonas, Amy O; de Oliveira Pena, Janethe; Humbert, Marc; Hoeper, Marius M
发表日期：2023
文献求助 收藏

Riociguat in patients with early diffuse cutaneous systemic sclerosis (RISE-SSc): randomised, double-blind, placebo-controlled multicentre trial

利奥西呱治疗早期弥漫性皮肤系统性硬化症患者（RISE-SSc）：一项随机、双盲、安慰剂对照的多中心试验

期刊:Annals of the Rheumatic Diseases
影响因子:20.6
doi:10.1136/annrheumdis-2019-216823
Khanna, Dinesh; Allanore, Yannick; Denton, Christopher P; Kuwana, Masataka; Matucci-Cerinic, Marco; Pope, Janet E; Atsumi, Tatsuya; Bečvář, Radim; Czirják, László; Hachulla, Eric; Ishii, Tomonori; Ishikawa, Osamu; Johnson, Sindhu R; De Langhe, Ellen; Stagnaro, Chiara; Riccieri, Valeria; Schiopu, Elena; Silver, Richard M; Smith, Vanessa; Steen, Virginia; Stevens, Wendy; Szücs, Gabriella; Truchetet, Marie-Elise; Wosnitza, Melanie; Laapas, Kaisa; de Oliveira Pena, Janethe; Yao, Zhen; Kramer, Frank; Distler, Oliver
系统性硬化症
免疫/内分泌
发表日期：2020
文献求助 收藏

Progressive skin fibrosis is associated with a decline in lung function and worse survival in patients with diffuse cutaneous systemic sclerosis in the European Scleroderma Trials and Research (EUSTAR) cohort

在欧洲硬皮病试验和研究（EUSTAR）队列中，进行性皮肤纤维化与弥漫性皮肤系统性硬化症患者的肺功能下降和生存率降低相关。

期刊:Annals of the Rheumatic Diseases
影响因子:20.6
doi:10.1136/annrheumdis-2018-213455
Wu, Wanlong; Jordan, Suzana; Graf, Nicole; de Oliveira Pena, Janethe; Curram, John; Allanore, Yannick; Matucci-Cerinic, Marco; Pope, Janet E; Denton, Christopher P; Khanna, Dinesh; Distler, Oliver
STAR
系统性硬化症
免疫/内分泌
发表日期：2019
文献求助 收藏