日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Payload Diversification Overcomes Resistance and Guides Sequential Antibody-Drug Conjugate Therapy in Breast Cancer.

有效载荷多样化克服耐药性并指导乳腺癌的序贯抗体药物偶联疗法。

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-25-3321
Rampa Dileep Reddy, Seo Minji, Ogata Nanae, Yang Zhaoxuan, Sridhar Nithya, Fujii Takeo, Wannaphut Chalothorn, Maynard Jennifer A, Tsuchikama Kyoji, Sledge George W Jr, Ueno Naoto T, Lee Jangsoon
肿瘤
肿瘤免疫
乳腺癌
发表日期：2026
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Mechanisms of resistance to trastuzumab deruxtecan in breast cancer elucidated by multi-omic molecular profiling

通过多组学分子谱分析阐明乳腺癌对曲妥珠单抗德鲁替康的耐药机制

期刊:NPJ Breast Cancer
影响因子:7.6
doi:10.1038/s41523-025-00868-y
Sledge, George W; Xiu, Joanne; Mahtani, Reshma L; Sandoval Leon, Ana C; Meric-Bernstam, Funda; Ribeiro, Jennifer R; Kulkarni, Ninad N; Rampa, Dileep R; Lee, Jangsoon; Ueno, Naoto T; Oberley, Matthew J; Radovich, Milan; Spetzler, David B
肿瘤
肿瘤免疫
乳腺癌
发表日期：2025
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Targeting CDK7 Enhances the Antitumor Efficacy of Enzalutamide in Androgen Receptor-Positive Triple-Negative Breast Cancer by Inhibiting c-MYC-mediated Tumorigenesis

靶向 CDK7 通过抑制 c-MYC 介导的肿瘤发生增强恩扎卢胺在雄激素受体阳性三阴性乳腺癌中的抗肿瘤疗效

期刊:Molecular Cancer Therapeutics
影响因子:5.3
doi:10.1158/1535-7163.MCT-23-0386
Xuemei Xie # ，Maroua Manai # ，Dileep R Rampa ，Jon A Fuson ，Elizabeth S Nakasone ，Troy Pearson ，Bharat S Kuntal ，Debu Tripathy ，Naoto T Ueno ，Jangsoon Lee
免疫/内分泌
CDK7
肿瘤
肿瘤免疫
乳腺癌
信号转导
MYC
发表日期：2025
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Dual Therapeutic Impact of AXL Inhibitor AB-329: Chemotherapy Sensitization and Immune Microenvironment Reprogramming in TNBC

AXL抑制剂AB-329的双重治疗作用：增强三阴性乳腺癌的化疗敏感性并重编程免疫微环境。

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26188896
Rampa, Dileep Reddy; Fuson, Jon A; Liu, Huey; Pan, Max; Qin, Yujia; Deng, Youping; Ueno, Naoto T; Lee, Jangsoon
肿瘤
肿瘤免疫
AXL
乳腺癌
免疫/内分泌
发表日期：2025
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Bioactive Compounds from Dodonaea viscosa Flowers: Potent Antibacterial and Antiproliferative Effects in Breast Cancer Cells.

来自粘毛狗尾草花的生物活性化合物：对乳腺癌细胞具有强大的抗菌和抗增殖作用

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules30112274
Raksat Achara, Yee Daniel, Gi Young Jin, Wongwiwatthananukit Supakit, Chang Leng Kar, Kaawaloa Kumu Piilani, Wall Marisa M, Lee Jangsoon, Chang Leng Chee
细胞生物学
乳腺癌
肿瘤免疫
发表日期：2025
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LMP7-Specific Inhibitor M3258 Modulates the Tumor Microenvironment of Triple-Negative Breast Cancer and Inflammatory Breast Cancer.

LMP7 特异性抑制剂 M3258 调节三阴性乳腺癌和炎性乳腺癌的肿瘤微环境

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers17111887
Xie Xuemei, Lee Jangsoon, Manyam Ganiraju C, Pearson Troy, Walter-Bausch Gina, Friese-Hamim Manja, Zhao Sheng, Jabs Julia, Manginelli Angela A, Piske Nadine, Mrowiec Thomas, Wolf Corinna M, Kuntal Bharat S, Tripathy Debu, Wang Jing, Sanderson Michael P, Ueno Naoto T
肿瘤
乳腺癌
肿瘤免疫
发表日期：2025
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Antibodies blocking PlGF or VEGF interactions with the NRP1 receptor mediate anti-proliferative effects

阻断PlGF或VEGF与NRP1受体相互作用的抗体介导抗增殖作用

期刊:
影响因子:
doi:10.1101/2025.10.25.684565
Blackman, Samuel A; Qerqez, Ahlam N; Lee, Alison G; Johnson, Nicole V; Owens, Justin M; Lai, Grace S; Aldrich, Emma C; Sprenger, Kayla G; Lee, Jangsoon; Verrier, Sophie; Stoddart, Martin J; Nguyen, Annalee W; Maynard, Jennifer A
信号转导
VEGF
EGF
NRP1
发表日期：2025
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The DNA repair pathway as a therapeutic target to synergize with trastuzumab deruxtecan in HER2-targeted antibody-drug conjugate-resistant HER2-overexpressing breast cancer

DNA 修复通路作为治疗靶点与曲妥珠单抗协同作用治疗 HER2 靶向抗体药物偶联物耐药 HER2 过表达乳腺癌

期刊:Journal of Experimental & Clinical Cancer Research
影响因子:11.4
doi:10.1186/s13046-024-03143-3
Jangsoon Lee #, Kumiko Kida #, Jiwon Koh, Huey Liu, Ganiraju C Manyam, Young Jin Gi, Dileep R Rampa, Asha S Multani, Jing Wang, Gitanjali Jayachandran, Dae-Won Lee, James M Reuben, Aysegul Sahin, Lei Huo, Debu Tripathy, Seock-Ah Im, Naoto T Ueno7
肿瘤
乳腺癌
发表日期：2024
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Phase 2 study of neoadjuvant enzalutamide and paclitaxel for luminal androgen receptor-enriched TNBC: Trial results and insights into "ARness"

新辅助恩扎卢胺和紫杉醇治疗管腔型雄激素受体富集型三阴性乳腺癌的 II 期研究：试验结果及对“ARness”的见解

期刊:Cell Reports Medicine
影响因子:10.6
doi:10.1016/j.xcrm.2024.101595
Lim, Bora; Seth, Sahil; Yam, Clinton; Huo, Lei; Fujii, Takeo; Lee, Jangsoon; Bassett, Roland; Nasser, Sara; Ravenberg, Lisa; White, Jason; Clayborn, Alyson; Guerra, Gil; Litton, Jennifer K; Damodaran, Senthil; Layman, Rachel; Valero, Vicente; Tripathy, Debasish; Lewis, Michael; Dobrolecki, Lacey E; Lei, Jonathan; Candelaria, Rosalind; Arun, Banu; Rauch, Gaiane; Zhao, Li; Zhang, Jianhua; Ding, Qingqing; Symmans, W Fraser; Chang, Jeffrey T; Thompson, Alastair M; Moulder, Stacy L; Ueno, Naoto T
肿瘤
肿瘤免疫
信号转导
乳腺癌
免疫/内分泌
发表日期：2024
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Identification of Kinase Targets for Enhancing the Antitumor Activity of Eribulin in Triple-Negative Breast Cell Lines

鉴定激酶靶点以增强 Eribulin 在三阴性乳腺细胞系中的抗肿瘤活性

期刊:Biomedicines
影响因子:3.9
doi:10.3390/biomedicines11030735
Xuemei Xie, Jangsoon Lee, Jon A Fuson, Huey Liu, Toshiaki Iwase, Kyuson Yun, Cori Margain, Debu Tripathy, Naoto T Ueno
肿瘤
乳腺癌
其它细胞
HTRF
发表日期：2023
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