日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeted knock-in of NCF1 cDNA into the NCF2 locus leads to myeloid phenotypic correction of p47 phox -deficient chronic granulomatous disease

将 NCF1 cDNA 靶向敲入 NCF2 基因座可导致 p47 phox 缺陷型慢性肉芽肿病的髓系表型校正

Kah Mun Siow, Merve Güngör, Dominik Wrona, Federica Raimondi, Oleksandr Pastukhov, Panagiotis Tsapogas, Timon Menzi, Michael Schmitz, Péter István Kulcsár, Gerald Schwank, Ansgar Schulz, Martin Jinek, Ute Modlich, Ulrich Siler, Janine Reichenbach

Gene editing of NCF1 loci is associated with homologous recombination and chromosomal rearrangements

NCF1 基因位点的基因编辑与同源重组和染色体重排有关

Federica Raimondi, Kah Mun Siow, Dominik Wrona, Carla Fuster-García, Oleksandr Pastukhov, Michael Schmitz, Katja Bargsten, Lucas Kissling, Daan C Swarts, Geoffroy Andrieux, Toni Cathomen, Ute Modlich, Martin Jinek, Ulrich Siler #, Janine Reichenbach #

Expression of a large coding sequence: Gene therapy vectors for Ataxia Telangiectasia

大编码序列的表达:毛细血管扩张性共济失调症的基因治疗载体

Tanja Hirch ,Nadine Brander ,Franziska Schenk ,Simon J Pöllmann ,Janine Reichenbach ,Ralf Schubert ,Ute Modlich

Membrane Dynamics and Organization of the Phagocyte NADPH Oxidase in PLB-985 Cells

PLB-985 细胞中吞噬细胞 NADPH 氧化酶的膜动力学和组织

Jérémy Joly, Elodie Hudik, Sandrine Lecart, Dirk Roos, Paul Verkuijlen, Dominik Wrona, Ulrich Siler, Janine Reichenbach, Oliver Nüsse, Sophie Dupré-Crochet

High Levels of IL-18 and IFN-γ in Chronically Inflamed Tissue in Chronic Granulomatous Disease

慢性肉芽肿病慢性炎症组织中 IL-18 和 IFN-γ 水平较高

Virginia Meda Spaccamela, Rocio G Valencia, Oleksandr Pastukhov, Andrea Duppenthaler, Matthias S Dettmer, Juliane Erb, Urs C Steiner, Sven Hillinger, Carsten Speckmann, Stephan Ehl, Janine Reichenbach, Ulrich Siler

Ikaros family zinc finger 1 regulates dendritic cell development and function in humans

Ikaros 家族锌指 1 调节人类树突状细胞的发育和功能

Urszula Cytlak, Anastasia Resteu, Delfien Bogaert, Hye Sun Kuehn, Thomas Altmann, Andrew Gennery, Graham Jackson, Attila Kumanovics, Karl V Voelkerding, Seraina Prader, Melissa Dullaers, Janine Reichenbach, Harry Hill, Filomeen Haerynck, Sergio D Rosenzweig, Matthew Collin, Venetia Bigley

Lentiviral gene therapy vector with UCOE stably restores function in iPSC-derived neutrophils of a CDG patient

带有 UCOE 的慢病毒基因治疗载体稳定恢复 CDG 患者 iPSC 衍生中性粒细胞的功能

Walther Haenseler, Elena Kuzmenko, Adjoa Smalls-Mantey, Cathy Browne, Reinhard Seger, William S James, Sally A Cowley, Janine Reichenbach, Ulrich Siler

Non-invasive near-infrared fluorescence imaging of the neutrophil response in a mouse model of transient cerebral ischaemia

利用非侵入性近红外荧光成像技术研究小鼠短暂性脑缺血模型中的中性粒细胞反应

Markus Vaas ,Gaby Enzmann ,Therese Perinat ,Ulrich Siler ,Janine Reichenbach ,Kai Licha ,Anja Kipar ,Markus Rudin ,Britta Engelhardt ,Jan Klohs

CRISPR/Cas9-generated p47phox-deficient cell line for Chronic Granulomatous Disease gene therapy vector development

CRISPR/Cas9 产生的 p47phox 缺陷细胞系用于慢性肉芽肿病基因治疗载体开发

Dominik Wrona, Ulrich Siler, Janine Reichenbach

Neutrophil oxidative burst activates ATM to regulate cytokine production and apoptosis

中性粒细胞氧化爆发激活 ATM 来调节细胞因子产生和细胞凋亡

C J Harbort, Paulo Vitor Soeiro-Pereira, Horst von Bernuth, Angela M Kaindl, Beatriz Tavares Costa-Carvalho, Antonio Condino-Neto, Janine Reichenbach, Joachim Roesler, Arturo Zychlinsky, Borko Amulic