日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Development of a novel secondary phenotypic screen to identify hits within the mycobacterial protein synthesis pipeline

开发一种新型的二级表型筛选方法,用于识别分枝杆菌蛋白质合成途径中的有效靶点。

Burke, Christopher; Jankute, Monika; Moynihan, Patrick; Gonzalez Del Rio, Ruben; Li, Xiaojun; Esquivias, Jorge; Lelièvre, Joël; Cox, Jonathan A G; Sacchettini, James; Besra, Gurdyal S

The hydrolase LpqI primes mycobacterial peptidoglycan recycling

水解酶LpqI启动分枝杆菌肽聚糖循环

Patrick J Moynihan, Ian T Cadby, Natacha Veerapen, Monika Jankute, Marialuisa Crosatti, Galina V Mukamolova, Andrew L Lovering, Gurdyal S Besra

The role of hydrophobicity in tuberculosis evolution and pathogenicity

疏水性在结核病演变和致病性中的作用

Jankute, Monika; Nataraj, Vijayashankar; Lee, Oona Y-C; Wu, Houdini H T; Ridell, Malin; Garton, Natalie J; Barer, Michael R; Minnikin, David E; Bhatt, Apoorva; Besra, Gurdyal S

Disruption of Mycobacterial AftB Results in Complete Loss of Terminal β(1 → 2) Arabinofuranose Residues of Lipoarabinomannan

分枝杆菌 AftB 基因的破坏导致脂阿拉伯甘露聚糖末端 β(1→2) 阿拉伯呋喃糖残基的完全丧失

Jankute, Monika; Alderwick, Luke J; Noack, Stephan; Veerapen, Natacha; Nigou, Jérôme; Besra, Gurdyal S

Redeployment-based drug screening identifies the anti-helminthic niclosamide as anti-myeloma therapy that also reduces free light chain production

基于药物重部署的筛选发现,抗蠕虫药物尼克酰胺可作为抗骨髓瘤疗法,同时还能减少游离轻链的产生。

Khanim, F L; Merrick, B A M E; Giles, H V; Jankute, M; Jackson, J B; Giles, L J; Birtwistle, J; Bunce, C M; Drayson, M T