日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structures of neurokinin 1 receptor in complex with Gq and Gs proteins reveal substance P binding mode and unique activation features

神经激肽 1 受体与 Gq 和 Gs 蛋白的复合物结构揭示了 P 物质的结合模式和独特的激活特征

Cristian Thom, Janosch Ehrenmann, Santiago Vacca, Yann Waltenspühl, Jendrik Schöppe, Ohad Medalia, Andreas Plückthun

Engineering of Challenging G Protein-Coupled Receptors for Structure Determination and Biophysical Studies

针对结构测定和生物物理研究的具有挑战性的 G 蛋白偶联受体的工程设计

Yann Waltenspühl, Janosch Ehrenmann, Christoph Klenk, Andreas Plückthun

Crystal structure of the human oxytocin receptor

人类催产素受体的晶体结构

Yann Waltenspühl, Jendrik Schöppe, Janosch Ehrenmann, Lutz Kummer, Andreas Plückthun

Crystal structures of the human neurokinin 1 receptor in complex with clinically used antagonists

人类神经激肽 1 受体与临床使用的拮抗剂复合物的晶体结构

Jendrik Schöppe #, Janosch Ehrenmann #, Christoph Klenk, Prakash Rucktooa, Marco Schütz, Andrew S Doré, Andreas Plückthun

A generic selection system for improved expression and thermostability of G protein-coupled receptors by directed evolution

通过定向进化提高 G 蛋白偶联受体表达和热稳定性的通用选择系统

Christoph Klenk, Janosch Ehrenmann, Marco Schütz, Andreas Plückthun

Directed evolution of G protein-coupled receptors in yeast for higher functional production in eukaryotic expression hosts

酵母中 G 蛋白偶联受体的定向进化可在真核表达宿主中实现更高的功能性生产

Marco Schütz, Jendrik Schöppe, Erik Sedlák, Matthias Hillenbrand, Gabriela Nagy-Davidescu, Janosch Ehrenmann, Christoph Klenk, Pascal Egloff, Lutz Kummer, Andreas Plückthun