A highly D(3)R-selective and efficacious partial agonist (S)-ABS01-113 compared to its D(3)R-selective antagonist enantiomer (R)-ABS01-113 as potential treatments for opioid use disorder
与D(3)R选择性拮抗剂对映体(R)-ABS01-113相比，高选择性且高效的D(3)R部分激动剂(S)-ABS01-113有望成为治疗阿片类药物使用障碍的潜在药物。
期刊:Neuropsychopharmacology
影响因子:7.1
doi:10.1038/s41386-022-01379-1
Galaj, Ewa; Bi, Guo-Hua; Klein, Benjamin; Hempel, Briana; Shaik, Anver Basha; Gogarnoiu, Emma S; Friedman, Jacob; Lam, Jenny; Rais, Rana; Reed, John F; Bloom, Shelley H; Swanson, Tracy L; Schmachtenberg, Jennifer L; Eshleman, Amy J; Janowsky, Aaron; Xi, Zheng-Xiong; Newman, Amy Hauck
