Deletion of accessory genes 3a, 3b, 5a or 5b from avian coronavirus infectious bronchitis virus induces an attenuated phenotype both in vitro and in vivo
从禽冠状病毒传染性支气管炎病毒中删除辅助基因3a、3b、5a或5b,可在体外和体内诱导减毒表型。
期刊:Journal of General Virology
影响因子:4.3
doi:10.1099/jgv.0.001130
Laconi, Andrea; van Beurden, Steven J; Berends, Alinda J; Krämer-Kühl, Annika; Jansen, Christine A; Spekreijse, Dieuwertje; Chénard, Gilles; Philipp, Hans-Christian; Mundt, Egbert; Rottier, Peter J M; Hélène Verheije, M