日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Transcriptomic Signatures of Immune Suppression and Cellular Dysfunction Distinguish Latent from Transcriptionally Active HIV-1 Infection in Dendritic Cells

免疫抑制和细胞功能障碍的转录组特征可区分树突状细胞中潜伏型和转录活跃型 HIV-1 感染

Man, Shirley; Jansen, Jade; Kootstra, Neeltje A; Geijtenbeek, Teunis B H

Transcriptomic HIV-1 reservoir profiling reveals a role for mitochondrial functionality in HIV-1 latency

HIV-1病毒库转录组分析揭示线粒体功能在HIV-1潜伏期中的作用

Man, Shirley; Jansen, Jade; Kroeze, Stefanie; Geijtenbeek, Teunis B H; Kootstra, Neeltje A

Synergistic Activity of Second Mitochondrial-Derived Activator of Caspases Mimetic with Toll-like Receptor 8 Agonist Reverses HIV-1-Latency and Enhances Antiviral Immunity.

第二种线粒体衍生的半胱天冬酶模拟激活剂与 Toll 样受体 8 激动剂的协同作用可逆转 HIV-1 潜伏期并增强抗病毒免疫力

Vlaming Killian E, Jansen Jade, de Bree Godelieve J, Kootstra Neeltje A, Geijtenbeek Teunis B H

Inducible HIV-1 Reservoir Reduction Assay (HIVRRA), a Fast and Sensitive Assay to Test Cytotoxicity and Potency of Cure Strategies to Reduce the Replication-Competent HIV-1 Reservoir in Ex Vivo PBMCs.

诱导型 HIV-1 病毒库减少试验 (HIVRRA) 是一种快速灵敏的试验,用于测试细胞毒性和治愈策略对减少体外 PBMC 中具有复制能力的 HIV-1 病毒库的效力

Jansen Jade, Geijtenbeek Teunis B H, Kootstra Neeltje A

Noncanonical-NF-κB activation and DDX3 inhibition reduces the HIV-1 reservoir by elimination of latently infected cells ex-vivo

非经典NF-κB激活和DDX3抑制可通过清除体外潜伏感染细胞来减少HIV-1病毒库。

Jansen, Jade; Kroeze, Stefanie; Man, Shirley; Andreini, Matteo; Bakker, Jan-Willem; Zamperini, Claudio; Tarditi, Alessia; Kootstra, Neeltje A; Geijtenbeek, Teunis B H