Residues T48 and A49 in HIV-1 NL4-3 Nef are responsible for the counteraction of autophagy initiation, which prevents the ubiquitin-dependent degradation of Gag through autophagosomes
HIV-1 NL4-3 Nef 中的残基 T48 和 A49 负责抑制自噬启动,从而阻止自噬体对 Gag 进行泛素依赖性降解
期刊:Retrovirology
影响因子:2.7
doi:10.1186/s12977-021-00576-y
Sergio Castro-Gonzalez, Yuexuan Chen, Jared Benjamin, Yuhang Shi, Ruth Serra-Moreno