日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Leiomodin 2 neonatal dilated cardiomyopathy mutation results in altered actin gene signatures and cardiomyocyte dysfunction

Leiomodin 2 新生儿扩张型心肌病突变导致肌动蛋白基因特征改变和心肌细胞功能障碍

Jessika B Iwanski, Christopher T Pappas, Rachel M Mayfield, Gerrie P Farman, Rebecca Ahrens-Nicklas, Jared M Churko, Carol C Gregorio

Surfaceome mapping of primary human heart cells with CellSurfer uncovers cardiomyocyte surface protein LSMEM2 and proteome dynamics in failing hearts

使用 CellSurfer 对原代人类心脏细胞进行表面组图谱绘制,揭示了心肌细胞表面蛋白 LSMEM2 和心脏衰竭中的蛋白质组动态

Linda Berg Luecke, Matthew Waas, Jack Littrell, Melinda Wojtkiewicz, Chase Castro, Maria Burkovetskaya, Erin N Schuette, Amanda Rae Buchberger, Jared M Churko, Upendra Chalise, Michelle Waknitz, Shelby Konfrst, Roald Teuben, Justin Morrissette-McAlmon, Claudius Mahr, Daniel R Anderson, Kenneth R Boh

The OM-85 bacterial lysate inhibits SARS-CoV-2 infection of epithelial cells by downregulating SARS-CoV-2 receptor expression

OM-85细菌裂解物通过下调SARS-CoV-2受体表达来抑制SARS-CoV-2对上皮细胞的感染。

Vadim Pivniouk ,Oksana Pivniouk ,Avery DeVries ,Jennifer L Uhrlaub ,Ashley Michael ,Denis Pivniouk ,Sydney R VanLinden ,Michelle Y Conway ,Seongmin Hahn ,Sean P Malone ,Peace Ezeh ,Jared M Churko ,Dayna Anderson ,Monica Kraft ,Janko Nikolich-Zugich ,Donata Vercelli

Development of Human Pituitary Neuroendocrine Tumor Organoids to Facilitate Effective Targeted Treatments of Cushing's Disease

开发人类垂体神经内分泌肿瘤类器官以促进库欣病的有效靶向治疗

Jayati Chakrabarti, Ritu Pandey, Jared M Churko, Jennifer Eschbacher, Saptarshi Mallick, Yuliang Chen, Beth Hermes, Palash Mallick, Ben N Stansfield, Kelvin W Pond, Curtis A Thorne, Kevin C J Yuen, Andrew S Little, Yana Zavros

Neonatal-lethal dilated cardiomyopathy due to a homozygous LMOD2 donor splice-site variant

因纯合 LMOD2 供体剪接位点变异导致的新生儿致死性扩张型心肌病

Michaela Yuen #, Lisa Worgan #, Jessika Iwanski, Christopher T Pappas, Himanshu Joshi, Jared M Churko, Susan Arbuckle, Edwin P Kirk, Ying Zhu, Tony Roscioli, Carol C Gregorio, Sandra T Cooper

Generation of an iPSC line from a Pontocerebellar Hypoplasia 1B patient harboring a homozygous c.395 A > C mutation in EXOSC3 along with a family matched control

从携带 EXOSC3 纯合 c.395 A > C 突变的 1B 型小脑桥脑发育不全患者及其家族匹配对照中生成 iPSC 系

Ben N Stansfield, Sampath Rangasamy, Keri Ramsey, May Khanna, Jared M Churko

MMP inhibitors attenuate doxorubicin cardiotoxicity by preventing intracellular and extracellular matrix remodelling

MMP 抑制剂通过阻止细胞内和细胞外基质重塑来减轻阿霉素的心脏毒性

Brandon Y H Chan, Andrej Roczkowsky, Woo Jung Cho, Mathieu Poirier, Consolato Sergi, Vic Keschrumrus, Jared M Churko, Henk Granzier, Richard Schulz

Antihypertensive drug treatment and susceptibility to SARS-CoV-2 infection in human PSC-derived cardiomyocytes and primary endothelial cells

抗高血压药物治疗和人类 PSC 衍生的心肌细胞和原代内皮细胞对 SARS-CoV-2 感染的易感性

Jessika Iwanski, Sobhi G Kazmouz, Shuaizhi Li, Ben Stansfield, Tori T Salem, Samantha Perez-Miller, Toshinobu Kazui, Lipsa Jena, Jennifer L Uhrlaub, Scott Lick, Janko Nikolich-Žugich, John P Konhilas, Carol C Gregorio, May Khanna, Samuel K Campos, Jared M Churko

Single-cell protein expression of hiPSC-derived cardiomyocytes using Single-Cell Westerns

使用单细胞 Westerns 对 hiPSC 衍生的心肌细胞进行单细胞蛋白表达

Eric Jabart, Josh Molho, Kristina Sin, Ben Stansfield, Sobhi G Kazmouz, Daniela Ventro, Kelly Gardner, Joseph C Wu, Jared M Churko

Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy

PDGF 通路激活将 LMNA 突变与扩张型心肌病联系起来

Jaecheol Lee #, Vittavat Termglinchan #, Sebastian Diecke #, Ilanit Itzhaki, Chi Keung Lam, Priyanka Garg, Edward Lau, Matthew Greenhaw, Timon Seeger, Haodi Wu, Joe Z Zhang, Xingqi Chen, Isaac Perea Gil, Mohamed Ameen, Karim Sallam, June-Wha Rhee, Jared M Churko, Rinkal Chaudhary, Tony Chour, Paul J