CDK4/6 inhibition enhances antitumor efficacy of chemotherapy and immune checkpoint inhibitor combinations in preclinical models and enhances T-cell activation in patients with SCLC receiving chemotherapy
CDK4/6 抑制可增强临床前模型中化疗和免疫检查点抑制剂联合治疗的抗肿瘤疗效，并增强接受化疗的小细胞肺癌患者的 T 细胞活化
期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.3
doi:10.1136/jitc-2020-000847
Anne Y Lai #, Jessica A Sorrentino #, Konstantin H Dragnev, Jared M Weiss, Taofeek K Owonikoko, Julie A Rytlewski, Jill Hood, Zhao Yang, Rajesh K Malik, Jay C Strum, Patrick J Roberts
信号转导
肿瘤
肺癌
T细胞
Functional/Block/Neutralize
Checkpoint
Mouse
PDCD1
