日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Design and characterization of a heterobifunctional degrader of KEAP1

KEAP1 异双功能降解剂的设计和表征

Hao Chen, Nghi H Nguyen, Charlene M Magtoto, Simon A Cobbold, Grace M Bidgood, Lizeth G Meza Guzman, Lachlan W Richardson, Jason Corbin, Amanda E Au, Bernhard C Lechtenberg, Rebecca Feltham, Kate D Sutherland, Christoph Grohmann, Sandra E Nicholson, Brad E Sleebs

The necroptotic cell death pathway operates in megakaryocytes, but not in platelet synthesis

坏死性细胞死亡途径在巨核细胞中起作用,但不在血小板合成中起作用

Diane Moujalled #, Pradnya Gangatirkar #, Maria Kauppi, Jason Corbin, Marion Lebois, James M Murphy, Najoua Lalaoui, Joanne M Hildebrand, John Silke, Warren S Alexander, Emma C Josefsson

A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction

MLKL 支架区域的错义突变导致致命的新生儿炎症和造血功能障碍

Joanne M Hildebrand #, Maria Kauppi #, Ian J Majewski, Zikou Liu, Allison J Cox, Sanae Miyake, Emma J Petrie, Michael A Silk, Zhixiu Li, Maria C Tanzer, Gabriela Brumatti, Samuel N Young, Cathrine Hall, Sarah E Garnish, Jason Corbin, Michael D Stutz, Ladina Di Rago, Pradnya Gangatirkar, Emma C Josef

Targeting platelets for improved outcome in KRAS-driven lung adenocarcinoma

靶向血小板以改善 KRAS 驱动的肺腺癌的预后

Stephanie R Hyslop, Marliese Alexander, Alesha A Thai, Ariena Kersbergen, Andrew J Kueh, Marco J Herold, Jason Corbin, Pradnya Gangatirkar, Ashley P Ng, Benjamin J Solomon, Warren S Alexander, Kate D Sutherland, Emma C Josefsson

TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice

TNFR1 依赖性细胞死亡导致 Sharpin 缺陷小鼠发生炎症

James A Rickard, Holly Anderton, Nima Etemadi, Ueli Nachbur, Maurice Darding, Nieves Peltzer, Najoua Lalaoui, Kate E Lawlor, Hannah Vanyai, Cathrine Hall, Aleks Bankovacki, Lahiru Gangoda, Wendy Wei-Lynn Wong, Jason Corbin, Chunzi Huang, Edward S Mocarski, James M Murphy, Warren S Alexander, Anne K