日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Phosphorylated Lamin A/C in the Nuclear Interior Binds Active Enhancers Associated with Abnormal Transcription in Progeria

核内部的磷酸化层蛋白 A/C 与早衰症中的异常转录相关的活性增强子结合

Kohta Ikegami, Stefano Secchia, Omar Almakki, Jason D Lieb, Ivan P Moskowitz

Tissue- and strain-specific effects of a genotoxic carcinogen 1,3-butadiene on chromatin and transcription

基因毒性致癌物 1,3-丁二烯对染色质和转录的组织和菌株特异性影响

Jennifer W Israel, Grace A Chappell, Jeremy M Simon, Sebastian Pott, Alexias Safi, Lauren Lewis, Paul Cotney, Hala S Boulos, Wanda Bodnar, Jason D Lieb, Gregory E Crawford, Terrence S Furey, Ivan Rusyn

A Transcriptional Lineage of the Early C. elegans Embryo

早期秀丽隐杆线虫胚胎的转录谱系

Sophia C Tintori, Erin Osborne Nishimura, Patrick Golden, Jason D Lieb, Bob Goldstein

Alterations to chromatin in intestinal macrophages link IL-10 deficiency to inappropriate inflammatory responses

肠道巨噬细胞染色质的改变将 IL-10 缺乏与不适当的炎症反应联系起来

Jeremy M Simon, James P Davis, Saangyoung E Lee, Matthew R Schaner, Gregory R Gipson, Matthew Weiser, R Balfour Sartor, Hans H Herfarth, Reza Rahbar, Timothy S Sadiq, Mark J Koruda, Dermot P McGovern, Jason D Lieb, Karen L Mohlke, Terrence S Furey, Shehzad Z Sheikh

STAT3 acts through pre-existing nucleosome-depleted regions bound by FOS during an epigenetic switch linking inflammation to cancer

在将炎症与癌症联系起来的表观遗传转换过程中,STAT3 通过 FOS 结合的预先存在的核小体耗尽区域发挥作用

Joseph D Fleming, Paul G Giresi, Marianne Lindahl-Allen, Elsa B Krall, Jason D Lieb, Kevin Struhl

Genome-wide analysis of human global and transcription-coupled excision repair of UV damage at single-nucleotide resolution

在单核苷酸分辨率下对人类整体和转录偶联切除紫外线损伤修复的全基因组分析

Jinchuan Hu, Sheera Adar, Christopher P Selby, Jason D Lieb, Aziz Sancar

Asymmetric transcript discovery by RNA-seq in C. elegans blastomeres identifies neg-1, a gene important for anterior morphogenesis

通过 RNA 测序在秀丽隐杆线虫胚泡中发现不对称转录本,鉴定出 neg-1,一种对前部形态发生很重要的基因

Erin Osborne Nishimura, Jay C Zhang, Adam D Werts, Bob Goldstein, Jason D Lieb

Genome-wide analysis links emerin to neuromuscular junction activity in Caenorhabditis elegans

全基因组分析将 Emerin 与秀丽隐杆线虫的神经肌肉接头活动联系起来

Cristina González-Aguilera, Kohta Ikegami, Cristina Ayuso, Alberto de Luis, María Íñiguez, Juan Cabello, Jason D Lieb, Peter Askjaer

Variation in chromatin accessibility in human kidney cancer links H3K36 methyltransferase loss with widespread RNA processing defects

人类肾癌中染色质可及性的变化与 H3K36 甲基转移酶的丢失和广泛的 RNA 加工缺陷有关

Jeremy M Simon, Kathryn E Hacker, Darshan Singh, A Rose Brannon, Joel S Parker, Matthew Weiser, Thai H Ho, Pei-Fen Kuan, Eric Jonasch, Terrence S Furey, Jan F Prins, Jason D Lieb, W Kimryn Rathmell, Ian J Davis

Quantitative genetics of CTCF binding reveal local sequence effects and different modes of X-chromosome association

CTCF 结合的数量遗传学揭示局部序列效应和 X 染色体关联的不同模式

Zhihao Ding, Yunyun Ni, Sander W Timmer, Bum-Kyu Lee, Anna Battenhouse, Sandra Louzada, Fengtang Yang, Ian Dunham, Gregory E Crawford, Jason D Lieb, Richard Durbin, Vishwanath R Iyer, Ewan Birney