日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A living organoid biobank of patients with Crohn's disease reveals molecular subtypes for personalized therapeutics

克罗恩病患者的活体类器官生物样本库揭示了分子亚型,可用于个性化治疗

Courtney Tindle ,Ayden G Fonseca ,Sahar Taheri ,Gajanan D Katkar ,Jasper Lee ,Priti Maity ,Ibrahim M Sayed ,Stella-Rita Ibeawuchi ,Eleadah Vidales ,Rama F Pranadinata ,Mackenzie Fuller ,Dominik L Stec ,Mahitha Shree Anandachar ,Kevin Perry ,Helen N Le ,Jason Ear ,Brigid S Boland ,William J Sandborn ,Debashis Sahoo ,Soumita Das ,Pradipta Ghosh

Complement receptor 3 is required for maximum in vitro trogocytic killing of the parasite Trichomonas vaginalis by human neutrophil-like cells

补体受体3是人中性粒细胞样细胞在体外最大程度吞噬杀灭阴道毛滴虫所必需的。

Emma N Trujillo ,Barbara A Flores ,Isabel V Romero ,Jose A Moran ,Aljona Leka ,Ashley D Ramirez ,Jason Ear ,Frances Mercer

Regulation of DNA damage response by trimeric G-proteins

三聚体 G 蛋白对 DNA 损伤反应的调节

Amer Ali Abd El-Hafeez, Nina Sun, Anirban Chakraborty, Jason Ear, Suchismita Roy, Pranavi Chamarthi, Navin Rajapakse, Soumita Das, Kathryn E Luker, Tapas K Hazra, Gary D Luker, Pradipta Ghosh

A long isoform of GIV/Girdin contains a PDZ-binding module that regulates localization and G-protein binding

GIV/Girdin 的长亚型含有 PDZ 结合模块,可调节定位和 G 蛋白结合

Jason Ear, Amer Ali Abd El-Hafeez, Suchismita Roy, Tony Ngo, Navin Rajapakse, Julie Choi, Soni Khandelwal, Majid Ghassemian, Luke McCaffrey, Irina Kufareva, Debashis Sahoo, Pradipta Ghosh

DAPLE protein inhibits nucleotide exchange on Gαs and Gαq via the same motif that activates Gαi

DAPLE 蛋白通过激活 Gαi 的相同基序抑制 Gαs 和 Gαq 上的核苷酸交换

Arthur Marivin, Marcin Maziarz, Jingyi Zhao, Vincent DiGiacomo, Isabel Olmos Calvo, Emily A Mann, Jason Ear, Juan B Blanco-Canosa, Elliott M Ross, Pradipta Ghosh, Mikel Garcia-Marcos

Two Isoforms of the Guanine Nucleotide Exchange Factor, Daple/CCDC88C Cooperate as Tumor Suppressors

鸟嘌呤核苷酸交换因子的两种同工型 Daple/CCDC88C 协同作为肿瘤抑制因子

Jason Ear, Ying Dunkel, Yash Mittal, Blaze B C Lim, Lawrence Liu, Magda K Holda, Ulrich Nitsche, Jorge Barbazán, Ajay Goel, Klaus-Peter Janssen, Nicolas Aznar, Pradipta Ghosh0

Convergence of Wnt, growth factor, and heterotrimeric G protein signals on the guanine nucleotide exchange factor Daple

Wnt、生长因子和异三聚体 G 蛋白信号在鸟嘌呤核苷酸交换因子 Daple 上的汇合

Nicolas Aznar, Jason Ear, Ying Dunkel, Nina Sun, Kendall Satterfield, Fang He, Nicholas A Kalogriopoulos, Inmaculada Lopez-Sanchez, Majid Ghassemian, Debashis Sahoo, Irina Kufareva, Pradipta Ghosh

Biochemical, Biophysical and Cellular Techniques to Study the Guanine Nucleotide Exchange Factor, GIV/Girdin

研究鸟嘌呤核苷酸交换因子 GIV/Girdin 的生化、生物物理和细胞技术

Pradipta Ghosh, Nicolas Aznar, Lee Swanson, I-Chung Lo, Inmaculada Lopez-Sanchez, Jason Ear, Cristina Rohena, Nicholas Kalogriopoulos, Linda Joosen, Ying Dunkel, Nina Sun, Peter Nguyen, Deepali Bhandari

Structural basis for activation of trimeric Gi proteins by multiple growth factor receptors via GIV/Girdin

多种生长因子受体通过 GIV/Girdin 激活三聚体 Gi 蛋白的结构基础

Changsheng Lin, Jason Ear, Krishna Midde, Inmaculada Lopez-Sanchez, Nicolas Aznar, Mikel Garcia-Marcos, Irina Kufareva, Ruben Abagyan, Pradipta Ghosh

The molecular basis of the Caskin1 and Mint1 interaction with CASK

Caskin1 和 Mint1 与 CASK 相互作用的分子基础

Ryan L Stafford, Jason Ear, Mary Jane Knight, James U Bowie