RAS nucleotide cycling underlies the SHP2 phosphatase dependence of mutant BRAF-, NF1- and RAS-driven cancers
RAS核苷酸循环是突变型BRAF、NF1和RAS驱动的癌症对SHP2磷酸酶依赖性的基础。
期刊:Nature Cell Biology
影响因子:19.1
doi:10.1038/s41556-018-0169-1
Nichols, Robert J; Haderk, Franziska; Stahlhut, Carlos; Schulze, Christopher J; Hemmati, Golzar; Wildes, David; Tzitzilonis, Christos; Mordec, Kasia; Marquez, Abby; Romero, Jason; Hsieh, Tientien; Zaman, Aubhishek; Olivas, Victor; McCoach, Caroline; Blakely, Collin M; Wang, Zhengping; Kiss, Gert; Koltun, Elena S; Gill, Adrian L; Singh, Mallika; Goldsmith, Mark A; Smith, Jacqueline A M; Bivona, Trever G
