Jason Lohmueller相关文献与解析，生知库 | 链接生命科学的每一步

CAR T cell infiltration and cytotoxic killing within the core of 3D breast cancer spheroids under the control of antigen sensing in microwell arrays

在微孔阵列中抗原感应的控制下，CAR-T 细胞在 3D 乳腺癌球体核心内浸润并进行细胞毒性杀伤

doi:10.1063/5.0207941

Youngbin Cho, Matthew S Laird, Teddi Bishop, Ruxuan Li, Dorota E Jazwinska, Elisa Ruffo, Jason Lohmueller, Ioannis K Zervantonakis

Post-translational covalent assembly of CAR and synNotch receptors for programmable antigen targeting

CAR和synNotch受体的翻译后共价组装用于可编程抗原靶向

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-023-37863-5.

Elisa Ruffo,Adam A Butchy,Yaniv Tivon,Victor So,Michael Kvorjak,Avani Parikh,Eric L Adams,Natasa Miskov-Zivanov,Olivera J Finn,Alexander Deiters,Jason Lohmueller

Metabolic reprogramming via an engineered PGC-1α improves human chimeric antigen receptor T-cell therapy against solid tumors

通过工程化的 PGC-1α 进行代谢重编程可改善针对实体肿瘤的人类嵌合抗原受体 T 细胞疗法

期刊:Journal for ImmunoTherapy of Cancer

影响因子:10.3

doi:10.1136/jitc-2022-006522

Konstantinos Lontos #, Yiyang Wang #, Supriya K Joshi, Andrew T Frisch, McLane J Watson, Alok Kumar, Ashley V Menk, Yupeng Wang, Rachel Cumberland, Jason Lohmueller, Esteban Carrizosa, Benjamin Boyerinas, Greg M Delgoffe

The costimulatory activity of Tim-3 requires Akt and MAPK signaling and its recruitment to the immune synapse

Tim-3 的共刺激活性需要 Akt 和 MAPK 信号传导及其募集到免疫突触

期刊:Science Signaling

影响因子:

doi:10.1126/scisignal.aba0717

Shunsuke Kataoka, Priyanka Manandhar, Judong Lee, Creg J Workman, Hridesh Banerjee, Andrea L Szymczak-Workman, Michael Kvorjak, Jason Lohmueller, Lawrence P Kane

Modeling recent human evolution in mice by expression of a selected EDAR variant

通过表达选定的 EDAR 变体在小鼠中模拟人类近期进化

期刊:Cell

影响因子:45.5

doi:10.1016/j.cell.2013.01.016

Yana G Kamberov, Sijia Wang, Jingze Tan, Pascale Gerbault, Abigail Wark, Longzhi Tan, Yajun Yang, Shilin Li, Kun Tang, Hua Chen, Adam Powell, Yuval Itan, Dorian Fuller, Jason Lohmueller, Junhao Mao, Asa Schachar, Madeline Paymer, Elizabeth Hostetter, Elizabeth Byrne, Melissa Burnett, Andrew P McMaho

The landscape of fitness effects of putatively functional noncoding mutations in humans

人类中假定具有功能性的非编码突变对适应性的影响图景

CAR T cell infiltration and cytotoxic killing within the core of 3D breast cancer spheroids under the control of antigen sensing in microwell arrays

在微孔阵列中抗原感应的控制下，CAR-T 细胞在 3D 乳腺癌球体核心内浸润并进行细胞毒性杀伤

Post-translational covalent assembly of CAR and synNotch receptors for programmable antigen targeting

CAR和synNotch受体的翻译后共价组装用于可编程抗原靶向

Metabolic reprogramming via an engineered PGC-1α improves human chimeric antigen receptor T-cell therapy against solid tumors

通过工程化的 PGC-1α 进行代谢重编程可改善针对实体肿瘤的人类嵌合抗原受体 T 细胞疗法

The costimulatory activity of Tim-3 requires Akt and MAPK signaling and its recruitment to the immune synapse

Tim-3 的共刺激活性需要 Akt 和 MAPK 信号传导及其募集到免疫突触

Modeling recent human evolution in mice by expression of a selected EDAR variant

通过表达选定的 EDAR 变体在小鼠中模拟人类近期进化