日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Increased condom use among key populations using oral PrEP in Kenya: results from large scale programmatic surveillance

肯尼亚重点人群口服PrEP使用者中安全套使用率增加:大规模项目监测结果

Manguro, Griffins O; Musau, Abednego M; Were, Daniel K; Tengah, Soud; Wakhutu, Brian; Reed, Jason; Plotkin, Marya; Luchters, Stanley; Gichangi, Peter; Temmerman, Marleen

An MHC-restricted antibody-based chimeric antigen receptor requires TCR-like affinity to maintain antigen specificity

基于 MHC 限制性抗体的嵌合抗原受体需要 TCR 样亲和力来维持抗原特异性

Marcela V Maus, Jason Plotkin, Gopinadh Jakka, Guillaume Stewart-Jones, Isabelle Rivière, Taha Merghoub, Jedd Wolchok, Christoph Renner, Michel Sadelain

Structural Design of Engineered Costimulation Determines Tumor Rejection Kinetics and Persistence of CAR T Cells

工程化共刺激的结构设计决定了CAR-T细胞的肿瘤排斥动力学和持久性

Zeguo Zhao,Maud Condomines,Sjoukje J C van der Stegen,Fabiana Perna,Christopher C Kloss,Gertrude Gunset,Jason Plotkin,Michel Sadelain

Regional delivery of mesothelin-targeted CAR T cell therapy generates potent and long-lasting CD4-dependent tumor immunity

区域递送间皮素靶向 CAR-T 细胞疗法可产生强效且持久的 CD4 依赖性肿瘤免疫力

Prasad S Adusumilli, Leonid Cherkassky, Jonathan Villena-Vargas, Christos Colovos, Elliot Servais, Jason Plotkin, David R Jones, Michel Sadelain

Chimeric antigen receptors combining 4-1BB and CD28 signaling domains augment PI3kinase/AKT/Bcl-XL activation and CD8+ T cell-mediated tumor eradication

结合 4-1BB 和 CD28 信号结构域的嵌合抗原受体可增强 PI3kinase/AKT/Bcl-XL 活化和 CD8+ T 细胞介导的肿瘤消除

Xiao-Song Zhong, Maiko Matsushita, Jason Plotkin, Isabelle Riviere, Michel Sadelain