日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Loss of GTF2I promotes neuronal apoptosis and synaptic reduction in human cellular models of neurodevelopment

在人类神经发育细胞模型中,GTF2I 的缺失会导致神经元凋亡和突触减少

Jason W Adams, Annabelle Vinokur, Janaína S de Souza, Charles Austria, Bruno S Guerra, Roberto H Herai, Karl J Wahlin, Alysson R Muotri

Impact of alcohol exposure on neural development and network formation in human cortical organoids

酒精暴露对人类皮质类器官神经发育和网络形成的影响

Jason W Adams, Priscilla D Negraes, Justin Truong, Timothy Tran, Ryan A Szeto, Bruno S Guerra, Roberto H Herai, Carmen Teodorof-Diedrich, Stephen A Spector, Miguel Del Campo, Kenneth L Jones, Alysson R Muotri, Cleber A Trujillo

Multimodal monitoring of human cortical organoids implanted in mice reveal functional connection with visual cortex

对小鼠植入的人类皮质类器官进行多模式监测,揭示其与视觉皮层的功能联系

Madison N Wilson #, Martin Thunemann #, Xin Liu, Yichen Lu, Francesca Puppo, Jason W Adams, Jeong-Hoon Kim, Mehrdad Ramezani, Donald P Pizzo, Srdjan Djurovic, Ole A Andreassen, Abed AlFatah Mansour, Fred H Gage, Alysson R Muotri, Anna Devor, Duygu Kuzum

Junctional instability in neuroepithelium and network hyperexcitability in a focal cortical dysplasia human model

局灶性皮质发育不良人类模型中的神经上皮连接不稳定性及网络兴奋性亢进

Simoni H Avansini, Francesca Puppo, Jason W Adams, Andre S Vieira, Ana C Coan, Fabio Rogerio, Fabio R Torres, Patricia A O R Araújo, Mariana Martin, Maria A Montenegro, Clarissa L Yasuda, Helder Tedeschi, Enrico Ghizoni, Andréa F E C França, Marina K M Alvim, Maria C Athié, Cristiane S Rocha, Vaness

SARS-CoV-2 infects human brain organoids causing cell death and loss of synapses that can be rescued by treatment with Sofosbuvir

SARS-CoV-2 会感染人脑类器官,导致细胞死亡和突触丢失,而索非布韦治疗可以挽救这些损伤。

Pinar Mesci,Janaina S de Souza,Laura Martin-Sancho,Angela Macia,Aurian Saleh,Xin Yin,Cedric Snethlage,Jason W Adams,Simoni H Avansini,Roberto H Herai,Angels Almenar-Queralt,Yuan Pu,Ryan A Szeto,Gabriela Goldberg,Patrick T Bruck,Fabio Papes,Sumit K Chanda,Alysson R Muotri

Pharmacological reversal of synaptic and network pathology in human MECP2-KO neurons and cortical organoids

药物逆转人类 MECP2-KO 神经元和皮质类器官中的突触和网络病理

Cleber A Trujillo, Jason W Adams, Priscilla D Negraes, Cassiano Carromeu, Leon Tejwani, Allan Acab, Ben Tsuda, Charles A Thomas, Neha Sodhi, Katherine M Fichter, Sarah Romero, Fabian Zanella, Terrence J Sejnowski, Henning Ulrich, Alysson R Muotri

Association of probable REM sleep behavior disorder with pathology and years of contact sports play in chronic traumatic encephalopathy

慢性创伤性脑病患者可能存在 REM 睡眠行为障碍,且与病理和多年的接触性运动有关

Jason W Adams, Michael L Alosco, Jesse Mez, Victor E Alvarez, Bertrand R Huber, Yorghos Tripodis, Charles H Adler, Carol Kubilius, Kerry A Cormier, Rebecca Mathais, Raymond Nicks, Hunter J Kelley, Nicole Saltiel, Madeline Uretsky, Evan Nair, Nurgul Aytan, Jonathan D Cherry, Christopher J Nowinski, N

Lewy Body Pathology and Chronic Traumatic Encephalopathy Associated With Contact Sports

与接触性运动相关的路易体病理学和慢性创伤性脑病

Jason W Adams, Victor E Alvarez, Jesse Mez, Bertrand R Huber, Yorghos Tripodis, Weiming Xia, Gaoyuan Meng, Caroline A Kubilus, Kerry Cormier, Patrick T Kiernan, Daniel H Daneshvar, Alicia S Chua, Sarah Svirsky, Raymond Nicks, Bobak Abdolmohammadi, Laney Evers, Todd M Solomon, Jonathan D Cherry, Nurg