Engineered extracellular vesicles-mediated curcumin delivery in brain microenvironment modulating lysosomes, mitochondria, and microglia reprogram for parkinson's disease therapy
利用工程化细胞外囊泡介导的姜黄素递送系统,在大脑微环境中调节溶酶体、线粒体和小胶质细胞的重编程,从而治疗帕金森病。
期刊:Journal of Nanobiotechnology
影响因子:12.6
doi:10.1186/s12951-025-03911-z
Shie, Ming-You; Chen, Mei-Chih; Chen, Yeh; Huang, Shi-Wei; Lin, Yen-Hong; Yu, Min-Hua; Pan, Chih-Ming; Chen, Cheng-Yu; Chen, Yi-Wen; Hsieh, Ching-Liang; Chiu, Shao-Chih; Kao, Shung-Te; Lin, Jaung-Geng; Cho, Der-Yang