日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Preclinical Studies of a Novel Human PD-1 B-Cell Peptide Cancer Vaccine PD1-Vaxx From BALB/c Mice to Beagle Dogs and to Non-Human Primates (Cynomolgus Monkeys)

新型人类 PD-1 B 细胞肽癌症疫苗 PD1-Vaxx 在 BALB/c 小鼠、比格犬和非人类灵长类动物(食蟹猴)中的临床前研究

Linlin Guo, Jay Overholser, Anthony J Good, Nicholas J Ede, Pravin T P Kaumaya

A newly discovered PD-L1 B-cell epitope peptide vaccine (PDL1-Vaxx) exhibits potent immune responses and effective anti-tumor immunity in multiple syngeneic mice models and (synergizes) in combination with a dual HER-2 B-cell vaccine (B-Vaxx)

新发现的 PD-L1 B 细胞表位肽疫苗 (PDL1-Vaxx) 在多种同基因小鼠模型中表现出强大的免疫反应和有效的抗肿瘤免疫力,并与双重 HER-2 B 细胞疫苗 (B-Vaxx) 联合使用(产生协同作用)

Linlin Guo, Jay Overholser, Heather Darby, Nicholas J Ede, Pravin T P Kaumaya

Immunogenicity and antitumor efficacy of a novel human PD-1 B-cell vaccine (PD1-Vaxx) and combination immunotherapy with dual trastuzumab/pertuzumab-like HER-2 B-cell epitope vaccines (B-Vaxx) in a syngeneic mouse model

新型人类 PD-1 B 细胞疫苗 (PD1-Vaxx) 和曲妥珠单抗/帕妥珠单抗样 HER-2 B 细胞表位双疫苗联合免疫疗法 (B-Vaxx) 在同基因小鼠模型中的免疫原性和抗肿瘤功效

Pravin T P Kaumaya, Linlin Guo, Jay Overholser, Manuel L Penichet, Tanios Bekaii-Saab

Anti-Tumor Effects of Peptide Therapeutic and Peptide Vaccine Antibody Co-targeting HER-1 and HER-2 in Esophageal Cancer (EC) and HER-1 and IGF-1R in Triple-Negative Breast Cancer (TNBC)

肽治疗和肽疫苗抗体共同靶向食管癌 (EC) 中的 HER-1 和 HER-2 以及三阴性乳腺癌 (TNBC) 中的 HER-1 和 IGF-1R 的抗肿瘤作用

Jay Overholser, Kristen Henkins Ambegaokar, Siobhan M Eze, Eduardo Sanabria-Figueroa, Rita Nahta, Tanios Bekaii-Saab, Pravin T P Kaumaya