日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discrete vulnerability to pharmacological CDK2 inhibition is governed by heterogeneity of the cancer cell cycle

癌细胞周期的异质性决定了药物 CDK2 抑制的敏感性

Vishnu Kumarasamy, Jianxin Wang, Michelle Roti, Yin Wan, Adam P Dommer, Hanna Rosenheck, Sivasankar Putta, Alec Trub, John Bisi, Jay Strum, Patrick Roberts, Seth M Rubin, Costakis Frangou, Karen McLean, Agnieszka K Witkiewicz, Erik S Knudsen

INX-315, a Selective CDK2 Inhibitor, Induces Cell Cycle Arrest and Senescence in Solid Tumors

INX-315 是一种选择性 CDK2 抑制剂,可诱导实体瘤细胞周期停滞和衰老。

Catherine Dietrich # ,Alec Trub # ,Antonio Ahn ,Michael Taylor ,Krutika Ambani ,Keefe T Chan ,Kun-Hui Lu ,Christabella A Mahendra ,Catherine Blyth ,Rhiannon Coulson ,Susanne Ramm ,April C Watt ,Sunil Kumar Matsa ,John Bisi ,Jay Strum ,Patrick Roberts ,Shom Goel

GSK983: a novel compound with broad-spectrum antiviral activity

GSK983:具有广谱抗病毒活性的新型化合物

Robert Harvey, Kevin Brown, Qin Zhang, Margaret Gartland, Leslie Walton, Christine Talarico, Wendell Lawrence, Dean Selleseth, Neil Coffield, Jeffry Leary, Kelly Moniri, Sara Singer, Jay Strum, Kristjan Gudmundsson, Karen Biron, Karen R Romines, Phiroze Sethna