日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Direct imaging with multidimensional labelling and high-content analysis allows quantitative categorization and characterizations of individual small extracellular vesicles and nanoparticles (sEVPs)

通过多维标记和高内涵分析的直接成像可以对单个小细胞外囊泡和纳米颗粒 (sEVP) 进行定量分类和表征

Simou Sun, Sarah J Cox-Vázquez, Nam-Joon Cho, Guillermo C Bazan, Jay T Groves

Bimodality in Ras signaling originates from processivity of the Ras activator SOS without deterministic bistability

Ras 信号中的双峰性源于 Ras 激活剂 SOS 的加工性,而没有确定性的双稳态性

Albert A Lee, Neil H Kim, Steven Alvarez, He Ren, Joseph B DeGrandchamp, L J Nugent Lew, Jay T Groves

Differential Roles of Kinetic On- and Off-Rates in T-Cell Receptor Signal Integration Revealed with a Modified Fab'-DNA Ligand

利用修饰的 Fab'-DNA 配体揭示 T 细胞受体信号整合中动力学结合率和解离率的不同作用

Kiera B Wilhelm, Anand Vissa, Jay T Groves

Stimulation of the catalytic activity of the tyrosine kinase Btk by the adaptor protein Grb2

衔接蛋白 Grb2 刺激酪氨酸激酶 Btk 的催化活性

Laura M Nocka, Timothy J Eisen, Anthony T Iavarone, Jay T Groves, John Kuriyan

Allosteric inhibition of the T cell receptor by a designed membrane ligand

通过设计的膜配体对T细胞受体进行变构抑制

Yujie Ye ,Shumpei Morita ,Justin J Chang ,Patrick M Buckley ,Kiera B Wilhelm ,Daniel DiMaio ,Jay T Groves ,Francisco N Barrera

Discrete LAT condensates encode antigen information from single pMHC:TCR binding events

离散的LAT凝聚体编码来自单个pMHC:TCR结合事件的抗原信息

Darren B McAffee ,Mark K O'Dair ,Jenny J Lin ,Shalini T Low-Nam ,Kiera B Wilhelm ,Sungi Kim ,Shumpei Morita ,Jay T Groves

Membrane-mediated dimerization potentiates PIP5K lipid kinase activity

膜介导的二聚化增强 PIP5K 脂质激酶活性

Scott D Hansen, Albert A Lee, Benjamin R Duewell, Jay T Groves

Competition for shared downstream signaling molecules establishes indirect negative feedback between EGFR and EphA2

EGFR 和 EphA2 之间对共享下游信号分子的竞争建立了间接负反馈

Dongmyung Oh, Zhongwen Chen, Kabir H Biswas, Funing Bai, Hui Ting Ong, Michael P Sheetz, Jay T Groves

EphrinB2 clustering by Nipah virus G is required to activate and trap F intermediates at supported lipid bilayer-cell interfaces

尼帕病毒G蛋白介导的EphrinB2聚集对于激活和捕获支持脂双层-细胞界面处的F中间体是必需的。

Joyce J Wong ,Zhongwen Chen ,Jean K Chung ,Jay T Groves ,Theodore S Jardetzky

Probing the effect of clustering on EphA2 receptor signaling efficiency by subcellular control of ligand-receptor mobility

通过亚细胞控制配体-受体迁移探索聚集对 EphA2 受体信号传导效率的影响

Zhongwen Chen #, Dongmyung Oh #, Kabir Hassan Biswas, Ronen Zaidel-Bar, Jay T Groves