Jean Christine相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Decoding the Integrated Stress Response of Pancreatic Cancer: Identifying a Serine-dependent Tumor Subset Under Metabolic Relationships With CAFs

解码胰腺癌的整合应激反应：识别与癌相关成纤维细胞代谢关系中的丝氨酸依赖性肿瘤亚群

期刊:Advanced Science

影响因子:14.1

doi:10.1002/advs.202515740

Shin, Sauyeun; Liauzun, Mehdi; Solorzano, Jacobo; Bras, Morgane Le; Jean, Christine; Fourneaux, Benjamin; Dore, Margaux; Fevrier, Lea; Belhabib, Ismahane; Brunel, Alexia; Neuzillet, Cindy; Larroque, Marion; Joffre, Carine; Rocchi, Stephane; Fraunhoffer, Nicolas; Perraud, Aurelie; Mathonnet, Muriel; Pancaldi, Vera; Linares, Laetitia; Iovanna, Juan; Dusetti, Nelson; Larsson, Ola; Nicolle, Remy; Pyronnet, Stephane; Bousquet, Corinne; Martineau, Yvan

成纤维细胞

细胞生物学

发表日期：2026

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Inducible FAK loss but not FAK inhibition in endothelial cells of PYK2-null mice activates p53 tumor suppressor to prevent tumor growth.

PYK2 基因敲除小鼠内皮细胞中 FAK 的诱导性缺失（而非 FAK 的抑制）可激活 p53 肿瘤抑制因子，从而阻止肿瘤生长

期刊:Molecular Biology of the Cell

影响因子:2.7

doi:10.1091/mbc.E24-12-0562

Chen Xiao Lei, Ojalill Marjaana, Jean Christine, Tancioni Isabelle, Jiang Shulin, Boyer Antonia, Ozmadenci Duygu, Uryu Sean, Tarin David, Schlessinger Joseph, Stupack Dwayne G, Schlaepfer David D

细胞生物学

发表日期：2025

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Inducible FAK Deletion but not FAK Inhibition in Endothelial Cells Activates p53 to Suppress Tumor Growth in PYK2-null Mice

内皮细胞中FAK的诱导性缺失而非FAK的抑制可激活p53，从而抑制PYK2基因敲除小鼠的肿瘤生长

doi:10.1101/2024.11.04.622008

Chen, Xiao Lei; Ojalill, Marjaana; Jean, Christine; Tancioni, Isabelle; Jiang, Shulin; Boyer, Antonia; Ozmadenci, Duygu; Uryu, Sean; Tarin, David; Schlessinger, Joseph; Stupack, Dwayne G; Schlaepfer, David D

细胞生物学

发表日期：2024

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The transcription factor hepatocyte nuclear factor 4A acts in the intestine to promote white adipose tissue energy storage

转录因子肝细胞核因子4A在肠道中发挥作用，促进白色脂肪组织能量储存。

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-021-27934-w

Romain Girard ,Sarah Tremblay ,Christophe Noll ,Stéphanie St-Jean ,Christine Jones ,Yves Gélinas ,Faïza Maloum-Rami ,Nathalie Perreault ,Mathieu Laplante ,André C Carpentier ,François Boudreau

细胞生物学

发表日期：2022

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Efficacy and Safety of Adalimumab in Conjunction With Surgery in Moderate to Severe Hidradenitis Suppurativa: The SHARPS Randomized Clinical Trial

阿达木单抗联合手术治疗中重度化脓性汗腺炎的疗效和安全性：SHARPS随机临床试验

期刊:Jama Surgery

影响因子:14.9

doi:10.1001/jamasurg.2021.3655

Bechara, Falk G; Podda, Maurizio; Prens, Errol P; Horváth, Barbara; Giamarellos-Bourboulis, Evangelos J; Alavi, Afsaneh; Szepietowski, Jacek C; Kirby, Joslyn; Geng, Ziqian; Jean, Christine; Jemec, Gregor B E; Zouboulis, Christos C

发表日期：2021

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Extracellular Matrices and Cancer-Associated Fibroblasts: Targets for Cancer Diagnosis and Therapy?

细胞外基质和癌症相关成纤维细胞：癌症诊断和治疗的靶点？

影响因子:4.4

doi:10.3390/cancers13143466

Belhabib, Ismahane; Zaghdoudi, Sonia; Lac, Claire; Bousquet, Corinne; Jean, Christine

成纤维细胞

细胞生物学

发表日期：2021

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FAK in cancer: mechanistic findings and clinical applications

FAK在癌症中的作用：机制研究及临床应用

期刊:Nature Reviews Cancer

影响因子:66.8

doi:10.1038/nrc3792

Sulzmaier, Florian J; Jean, Christine; Schlaepfer, David D

发表日期：2014

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Inhibition of endothelial FAK activity prevents tumor metastasis by enhancing barrier function.

抑制内皮细胞 FAK 活性可通过增强屏障功能来阻止肿瘤转移

期刊:Journal of Cell Biology

影响因子:6.4

doi:10.1083/jcb.201307067

Jean Christine, Chen Xiao Lei, Nam Ju-Ock, Tancioni Isabelle, Uryu Sean, Lawson Christine, Ward Kristy K, Walsh Colin T, Miller Nichol L G, Ghassemian Majid, Turowski Patric, Dejana Elisabetta, Weis Sara, Cheresh David A, Schlaepfer David D

细胞生物学

发表日期：2014

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FAK Inhibition disrupts a β5 integrin signaling axis controlling anchorage-independent ovarian carcinoma growth

FAK抑制会破坏控制卵巢癌细胞非依赖性生长的β5整合素信号通路。

期刊:Molecular Cancer Therapeutics

影响因子:5.5

doi:10.1158/1535-7163.MCT-13-1063

Tancioni, Isabelle; Uryu, Sean; Sulzmaier, Florian J; Shah, Nina R; Lawson, Christine; Miller, Nichol L G; Jean, Christine; Chen, Xiao Lei; Ward, Kristy K; Schlaepfer, David D

细胞生物学

发表日期：2014

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VEGF-induced vascular permeability is mediated by FAK

VEGF 诱导的血管通透性由 FAK 介导

期刊:Developmental Cell

影响因子:10.7

doi:10.1016/j.devcel.2011.11.002

Xiao Lei Chen, Ju-Ock Nam, Christine Jean, Christine Lawson, Colin T Walsh, Erik Goka, Ssang-Taek Lim, Alok Tomar, Isabelle Tancioni, Sean Uryu, Jun-Lin Guan, Lisette M Acevedo, Sara M Weis, David A Cheresh, David D Schlaepfer

发表日期：2012

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