日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pharmacokinetics of Belumosudil and Its Metabolites in Individuals With Hepatic Impairment

贝鲁莫舒地尔及其代谢物在肝功能受损患者体内的药代动力学

Schueller, Olivier; Esposito, Virginie; Lohmer, Lauren; Beck, Felix; Teichert, Lenore; Patel, Jeegar; Sahi, Jasminder

In Vitro and Clinical Evaluations of UGT1A1-, P-gp-, OATP1B1-, and BCRP-Mediated Drug-Drug Interactions of Belumosudil, a Potent ROCK2 Inhibitor.

Belumosudil(一种强效 ROCK2 抑制剂)的 UGT1A1、P-gp、OATP1B1 和 BCRP 介导的药物相互作用的体外和临床评价

Schueller Olivier, Lohmer Lauren, Beck Felix, Patel Jeegar, Sahi Jasminder

Evaluation of the clinical molecule anti-human-PD-L1/IL-15 KD033 in the human-PD-1/PD-L1-expressing murine model demonstrates PD-L1 targeting of IL-15 in vivo

在人 PD-1/PD-L1 表达小鼠模型中对临床分子抗人 PD-L1/IL-15 KD033 的评估表明,PD-L1 在体内靶向 IL-15

Stella A Martomo, Jeegar Patel

Inhibition of glucose transport synergizes with chemical or genetic disruption of mitochondrial metabolism and suppresses TCA cycle-deficient tumors

抑制葡萄糖转运与化学或遗传破坏线粒体代谢产生协同作用,抑制 TCA 循环缺陷型肿瘤

Kellen Olszewski, Anthony Barsotti, Xiao-Jiang Feng, Milica Momcilovic, Kevin G Liu, Ji-In Kim, Koi Morris, Christophe Lamarque, Jack Gaffney, Xuemei Yu, Jeegar P Patel, Joshua D Rabinowitz, David B Shackelford, Masha V Poyurovsky

Functional antibody characterization via direct structural analysis and information-driven protein-protein docking

通过直接结构分析和信息驱动的蛋白质-蛋白质对接进行功能抗体表征

Rafael S Depetris, Dan Lu, Zhanna Polonskaya, Zhikai Zhang, Xenia Luna, Amari Tankard, Pegah Kolahi, Michael Drummond, Chris Williams, Maximilian C C J C Ebert, Jeegar P Patel, Masha V Poyurovsky

ROCK2 Inhibition With Belumosudil (KD025) for the Treatment of Chronic Graft-Versus-Host Disease

使用 Belumosudil (KD025) 抑制 ROCK2 治疗慢性移植物抗宿主病

Jagasia, Madan; Lazaryan, Aleksandr; Bachier, Carlos R; Salhotra, Amandeep; Weisdorf, Daniel J; Zoghi, Behyar; Essell, James; Green, Laurie; Schueller, Olivier; Patel, Jeegar; Zanin-Zhorov, Alexandra; Weiss, Jonathan M; Yang, Zhongming; Eiznhamer, David; Aggarwal, Sanjay K; Blazar, Bruce R; Lee, Stephanie J

Single-Dose Anti-PD-L1/IL-15 Fusion Protein KD033 Generates Synergistic Antitumor Immunity with Robust Tumor-Immune Gene Signatures and Memory Responses

单剂量抗 PD-L1/IL-15 融合蛋白 KD033 产生协同抗肿瘤免疫力,并具有强大的肿瘤免疫基因特征和记忆反应

Stella A Martomo, Dan Lu, Zhanna Polonskaya, Xenia Luna, Zhikai Zhang, Sam Feldstein, Radovan Lumban-Tobing, Danielle K Almstead, Faical Miyara, Jeegar Patel

Evaluation of surface roughness of the bracket slot floor--a 3D perspective study

支架槽底表面粗糙度评估——三维视角研究

Agarwal, Chetankumar O; Vakil, Ketan K; Mahamuni, Avinash; Tekale, Pawankumar Dnyandeo; Gayake, Prasad V; Vakil, Jeegar K

Modulation of neuronal CXCR4 by the micro-opioid agonist DAMGO

微阿片类激动剂 DAMGO 对神经元 CXCR4 的调节

Jeegar P Patel, Rajarshi Sengupta, Giuseppe Bardi, Muhammad Z Khan, Anna Mullen-Przeworski, Olimpia Meucci

Human immunodeficiency virus gp120-induced apoptosis of human neuroblastoma cells in the absence of CXCR4 internalization

人类免疫缺陷病毒gp120在不发生CXCR4内化的情况下诱导人类神经母细胞瘤细胞凋亡

Bardi, Giuseppe; Sengupta, Rajarshi; Khan, Muhammad Z; Patel, Jeegar P; Meucci, Olimpia