日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Cyclic GMP-AMP synthase deficiency predisposes the liver to alcohol-induced cell death and ER stress

环磷酸鸟苷-AMP合成酶缺乏会使肝脏更容易受到酒精诱导的细胞死亡和内质网应激的影响。

期刊:Hepatology Communications
影响因子:4.6
doi:10.1097/HC9.0000000000000908
Babuta, Mrigya; Datta, Aditi Ashish; de Carvalho Ribeiro, Marcelle; Santos, Bruna de Araújo Cardoso Dos; Morel, Caroline; Copeland, Christopher; Ortega-Ribera, Marti; Mehta, Jeeval; Calenda, Charles; Wang, Yanbo; Remotti, Victoria; Brezani, Viliam; Patel, Arman; Hawryluk, Danielle; Szabo, Gyongyi
细胞生物学
内质网应激
发表日期：2026
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Neutrophil extracellular traps activate hepatic stellate cells and monocytes via NLRP3 sensing in alcohol-induced acceleration of MASH fibrosis

中性粒细胞胞外陷阱通过NLRP3感应激活肝星状细胞和单核细胞，从而加速酒精诱导的MASH纤维化。

期刊:Gut
影响因子:25.8
doi:10.1136/gutjnl-2023-331447
Babuta, Mrigya; Morel, Caroline; de Carvalho Ribeiro, Marcelle; Calenda, Charles; Ortega-Ribera, Martí; Thevkar Nagesh, Prashanth; Copeland, Christopher; Zhuang, Yuan; Wang, Yanbo; Cho, Yeonhee; Joshi, Radhika; Brezani, Viliam; Hawryluk, Danielle; Datta, Aditi Ashish; Mehta, Jeeval; Nasser, Imad; Szabo, Gyongyi
中性粒细胞
粒细胞
LRP3
单核细胞
NLRP3
细胞生物学
发表日期：2024
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Bile acid-induced IRF3 phosphorylation mediates cell death, inflammatory responses, and fibrosis in cholestasis-induced liver and kidney injury via regulation of ZBP1

胆汁酸诱导的IRF3磷酸化通过调节ZBP1介导胆汁淤积引起的肝肾损伤中的细胞死亡、炎症反应和纤维化。

期刊:Hepatology
影响因子:15.8
doi:10.1097/HEP.0000000000000611
Zhuang, Yuan; Ortega-Ribera, Martí; Thevkar Nagesh, Prashanth; Joshi, Radhika; Huang, Huihui; Wang, Yanbo; Zivny, Adam; Mehta, Jeeval; Parikh, Samir M; Szabo, Gyongyi
IRF3
炎症
炎症/感染
信号转导
ZBP1
肾损伤
磷酸化
细胞生物学
毒理研究
发表日期：2024
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In vivo Bruton's tyrosine kinase inhibition attenuates alcohol-associated liver disease by regulating CD84-mediated granulopoiesis

体内布鲁顿酪氨酸激酶抑制剂通过调节CD84介导的粒细胞生成来减轻酒精相关性肝病

期刊:Science Translational Medicine
影响因子:14.6
doi:10.1126/scitranslmed.adg1915
Nagesh, Prashanth Thevkar; Cho, Yeonhee; Zhuang, Yuan; Babuta, Mrigya; Ortega-Ribera, Marti; Joshi, Radhika; Brezani, Veronika; Patel, Arman; Datta, Aditi Ashish; Brezani, Viliam; Hsieh, Yun-Cheng; Ramos, Adriana; Mehta, Jeeval; Copeland, Christopher; Kanata, Eleni; Jiang, Zhenghui Gordon; Vlachos, Ioannis; Asara, John; Szabo, Gyongyi
T细胞
信号转导
CD8
粒细胞
CD84
细胞生物学
发表日期：2024
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Combined Insults of a MASH Diet and Alcohol Binges Activate Intercellular Communication and Neutrophil Recruitment via the NLRP3-IL-1β Axis in the Liver

MASH饮食和酒精暴饮的联合作用会通过肝脏中的NLRP3-IL-1β轴激活细胞间通讯和中性粒细胞募集

期刊:Cells
影响因子:5.1
doi:10.3390/cells13110960
Mrigya Babuta ，Prashanth Thevkar Nagesh ，Aditi Ashish Datta ，Victoria Remotti ，Yuan Zhuang ，Jeeval Mehta ，Francesca Lami ，Yanbo Wang ，Gyongyi Szabo
中性粒细胞
NLRP3
粒细胞
细胞生物学
LRP3
IL-1β
发表日期：2024
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Protective role of cGAS in NASH is related to the maintenance of intestinal homeostasis

cGAS在NASH中的保护作用与维持肠道稳态有关。

期刊:Liver International
影响因子:6
doi:10.1111/liv.15610
Marcelle de Carvalho Ribeiro ，Yeonhee Cho ，Jeeval Mehta ，Xiaojing Wang ，Mrigya Babuta ，Christopher Copeland ，Hosni Hussein ，Donna Catalano ，Yanbo Wang ，Gyongyi Szabo
发表日期：2023
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Pharmacological Inhibition of CCR2/5 Signaling Prevents and Reverses Alcohol-Induced Liver Damage, Steatosis, and Inflammation in Mice

药理学抑制CCR2/5信号通路可预防和逆转小鼠酒精性肝损伤、脂肪变性和炎症

期刊:Hepatology
影响因子:15.8
doi:10.1002/hep.30249
Ambade, Aditya; Lowe, Patrick; Kodys, Karen; Catalano, Donna; Gyongyosi, Benedek; Cho, Yeonhee; Iracheta-Vellve, Arvin; Adejumo, Adeyinka; Saha, Banishree; Calenda, Charles; Mehta, Jeeval; Lefebvre, Eric; Vig, Pamela; Szabo, Gyongyi
CR2
炎症
炎症/感染
信号转导
Immunology/Inflammation
肝损伤
毒理研究
发表日期：2019
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