日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

C端HSP90抑制剂NCT-58可削弱三阴性乳腺癌(TNBC)的癌干细胞样表型并增强化疗疗效。

Jung, Eunsun; Kim, Yoon-Jae; Lee, Kyoungmin; Jang, Seojin; Park, Soeun; Oh, Eunhye; Park, Minsu; Kim, Seongjae; Ko, Dongmi; Kang, Yong Koo; Nam, Kee Dal; Farrand, Lee; Nguyen, Cong-Truong; La, Minh Thanh; Ann, Jihyae; Lee, Jeewoo; Kim, Ji Young; Seo, Jae Hong

Impact of CYP2D6 Metabolizer Status on Ondansetron Efficacy in Early Pregnancy Induced Nausea and Vomiting: A Case Control Study

CYP2D6代谢状态对昂丹司琼治疗早期妊娠恶心呕吐疗效的影响:一项病例对照研究

Liu, Michelle; Shuey, Megan M; Holley, Sabrina E; Fountain, Darlene F; Jaworski, James; Griffin, Carol; Kim, Jeewoo; Stec, Melissa; Sunthankar, Sudeep D; Ong, Henry H; Gangireddy, Srushti; Wei, Wei-Qi; Gaedigk, Andrea; Velez Edwards, Digna R; Kawai, Vivian K

Genome-wide meta-analysis identifies novel risk loci for uterine fibroids within and across multiple ancestry groups

全基因组荟萃分析在多个祖先群体内部和之间发现了子宫肌瘤的新风险位点

Kim, Jeewoo; Williams, Ariel; Noh, Hannah; Jasper, Elizabeth A; Jones, Sarah H; Jaworski, James A; Shuey, Megan M; Ruiz-Narváez, Edward A; Wise, Lauren A; Palmer, Julie R; Connolly, John; Keaton, Jacob M; Denny, Joshua C; Khan, Atlas; Abbass, Mohammad A; Rasmussen-Torvik, Laura J; Kottyan, Leah C; Madhivanan, Purnima; Krupp, Karl; Wei, Wei-Qi; Edwards, Todd L; Velez Edwards, Digna R; Hellwege, Jacklyn N

Genomics-informed drug-repurposing strategy identifies two therapeutic targets for preventing liver disease associated with metabolic dysfunction

基于基因组学的药物重定位策略确定了两个可用于预防与代谢功能障碍相关的肝脏疾病的治疗靶点

Seagle, Hannah M; Akerele, Alexis T; DeCorte, Joseph A; Hellwege, Jacklyn N; Breeyear, Joseph H; Kim, Jeewoo; Levin, Michael G; Khodursky, Samuel; Bress, Adam; Lee, Kyung Min; Meiler, Jens; Gill, Dipender; Lee, Jennifer S; Heberer, Kent; Miller, Donald R; Reaven, Peter D; Chang, Kyong-Mi; Lynch, Julie A; Khankari, Nikhil K; Shuey, Megan M; Edwards, Todd L; Vujkovic, Marijana

An evidence-based framework for postoperative surveillance of meningioma

基于循证医学的脑膜瘤术后监测框架

Owusu-Adjei, Brittany; Lim, Jeewoo C; Hou, Connie C; Mietus, Constance J; Daci, Rrita; Lambert, William; Qureshi, Hanya; Berry, Bethany C; Marasco, Madison R B; Paul, Umika; Sirianni, Rachael W; Johnson, Mark D

Discovery of a Novel Multitarget Analgesic Through an In Vivo-Guided Approach

通过体内引导方法发现新型多靶点镇痛药

Guo Zhen, Nayeon Do, Nguyen Van Manh, Hee-Jin Ha, Hee Kim, Hyunsoo Kim, Kwanghyun Choi, Jihyae Ann, Jeewoo Lee

Genomics-Informed Drug Repurposing Strategy Identifies Novel Therapeutic Targets for Metabolic Dysfunction-Associated Steatotic Liver Disease

基于基因组学的药物重定位策略揭示了代谢功能障碍相关脂肪肝疾病的新治疗靶点

Seagle, Hannah M; Akerele, Alexis T; DeCorte, Joseph A; Hellwege, Jacklyn N; Breeyear, Joseph H; Kim, Jeewoo; Levin, Michael; Khodurksy, Samuel; Bress, Adam; Lee, Kyung; Meiler, Jens; Gill, Dipender; Lee, Jennifer S; Heberer, Kent; Miller, Donald R; Reaven, Peter; Chang, Kyong-Mi; Lynch, Julie A; Khankari, Nikhil K; Shuey, Megan M; Edwards, Todd L; Vujkovic, Marijana

Uterine fibroids show evidence of shared genetic architecture with blood pressure traits

子宫肌瘤与血压特征显示出共同的遗传结构。

Akerele, Alexis T; Piekos, Jacqueline A; Kim, Jeewoo; Khankari, Nikhil K; Hellwege, Jacklyn N; Edwards, Todd L; Velez Edwards, Digna R

Immunophenotypic and Transcriptomic Analysis of Peripheral Blood Mononuclear Cells in Bullous Pemphigoid

大疱性类天疱疮患者外周血单核细胞的免疫表型和转录组分析

Choi, Jeewoo; Nam, Jae-Yong; Kim, Min Sung; Choi, You Won; Choi, Hae Young; Byun, Ji Yeon

The HSP90 inhibitor HVH-2930 exhibits potent efficacy against trastuzumab-resistant HER2-positive breast cancer

HSP90 抑制剂 HVH-2930 对曲妥珠单抗耐药的 HER2 阳性乳腺癌表现出强效疗效

Minsu Park, Eunsun Jung, Jung Min Park, Soeun Park, Dongmi Ko, Juyeon Seo, Seongjae Kim, Kee Dal Nam, Yong Koo Kang, Lee Farrand, Van-Hai Hoang, Cong-Truong Nguyen, Minh Thanh La, Gibeom Nam, Hyun-Ju Park, Jihyae Ann, Jeewoo Lee, Yoon-Jae Kim, Ji Young Kim, Jae Hong Seo