日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

53BP1 loss elicits cGAS-STING-dependent antitumor immunity in ovarian and pancreatic cancer

53BP1 缺失在卵巢癌和胰腺癌中引发 cGAS-STING 依赖性抗肿瘤免疫

Yajie Sun #, Jeffrey Patterson-Fortin #, Sen Han, Zhe Li, Zuzanna Nowicka, Yuna Hirohashi, Susan Kilgas, Jae Kyo Yi, Alexander Spektor, Wojciech Fendler, Panagiotis A Konstantinopoulos, Dipanjan Chowdhury

Novobiocin blocks nucleic acid binding to Polθ and inhibits stimulation of its ATPase activity

新生霉素阻断核酸与 Polθ 结合并抑制其 ATPase 活性的刺激

Aleem Syed, Frantisek Filandr, Jeffrey Patterson-Fortin, Albino Bacolla, Ramya Ravindranathan, Jia Zhou, Drew T McDonald, Mohammed E Albuhluli, Amy Verway-Cohen, Joseph A Newman, Miaw-Sheue Tsai, Darin E Jones, David C Schriemer, Alan D D'Andrea, John A Tainer

Polymerase θ inhibition activates the cGAS-STING pathway and cooperates with immune checkpoint blockade in models of BRCA-deficient cancer

聚合酶θ抑制可激活cGAS-STING通路并与BRCA缺陷癌症模型中的免疫检查点阻断协同作用

Jeffrey Patterson-Fortin, Heta Jadhav, Constantia Pantelidou, Tin Phan, Carter Grochala, Anita K Mehta, Jennifer L Guerriero, Gerburg M Wulf, Brian M Wolpin, Ben Z Stanger, Andrew J Aguirre, James M Cleary, Alan D D'Andrea, Geoffrey I Shapiro

Targeting DNA Repair with Combined Inhibition of NHEJ and MMEJ Induces Synthetic Lethality in TP53-Mutant Cancers

靶向 DNA 修复并联合抑制 NHEJ 和 MMEJ 可在 TP53 突变癌症中诱导合成致死率

Jeffrey Patterson-Fortin, Arindam Bose, Wei-Chih Tsai, Carter Grochala, Huy Nguyen, Jia Zhou, Kalindi Parmar, Jean-Bernard Lazaro, Joyce Liu, Kelsey McQueen, Geoffrey I Shapiro, David Kozono, Alan D D'Andrea

Enhanced Detection of Short-Chain Fatty Acids Using Gas Chromatography Mass Spectrometry

使用气相色谱质谱法增强短链脂肪酸的检测

Haiwei Gu, Paniz Jasbi, Jeffrey Patterson, Yan Jin

Peripheral subcutaneous field stimulation for the treatment of spinal cord injury at-level pain: case report, literature review, and 5-year follow-up

外周皮下电场刺激治疗脊髓损伤节段疼痛:病例报告、文献综述及5年随访

Stabingas, Kristen; Bergman, Jeffrey; Patterson, Michael; Tomycz, Nestor D

A BRISC-SHMT complex deubiquitinates IFNAR1 and regulates interferon responses

BRISC-SHMT 复合物使 IFNAR1 去泛素化并调节干扰素反应

Hui Zheng, Vibhor Gupta, Jeffrey Patterson-Fortin, Sabyasachi Bhattacharya, Kanstantsin Katlinski, Junmin Wu, Bentley Varghese, Christopher J Carbone, Bernadette Aressy, Serge Y Fuchs, Roger A Greenberg

Differential regulation of JAMM domain deubiquitinating enzyme activity within the RAP80 complex

RAP80 复合物中 JAMM 结构域去泛素化酶活性的差异调节

Jeffrey Patterson-Fortin, Genze Shao, Heidi Bretscher, Troy E Messick, Roger A Greenberg

MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to DNA double-strand breaks

MERIT40 控制 BRCA1-Rap80 复合物的完整性和 DNA 双链断裂的募集

Genze Shao, Jeffrey Patterson-Fortin, Troy E Messick, Dan Feng, Niraj Shanbhag, Yingqun Wang, Roger A Greenberg