The Group B Streptococcal surface antigen I/II protein, BspC, interacts with host vimentin to promote adherence to brain endothelium and inflammation during the pathogenesis of meningitis
B族链球菌表面抗原I/II蛋白BspC与宿主波形蛋白相互作用,促进细菌黏附于脑内皮细胞,并在脑膜炎发病过程中引发炎症。
期刊:PLoS Pathogens
影响因子:4.9
doi:10.1371/journal.ppat.1007848
Deng, Liwen; Spencer, Brady L; Holmes, Joshua A; Mu, Rong; Rego, Sara; Weston, Thomas A; Hu, Yoonsung; Sanches, Glenda F; Yoon, Sunghyun; Park, Nogi; Nagao, Prescilla E; Jenkinson, Howard F; Thornton, Justin A; Seo, Keun Seok; Nobbs, Angela H; Doran, Kelly S