日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Single-cell transcriptomics of acetaminophen-induced responses in human 2D and 3D liver microtissues

对乙酰氨基酚诱导的人类二维和三维肝脏微组织反应的单细胞转录组学研究

期刊:Archives of Toxicology
影响因子:6.9
doi:10.1007/s00204-025-04296-6
Bwanya, Brian; Verheijen, Marcha C T; Hauser, Duncan; de Kok, Theo M; Jennen, Danyel G J; van den Beucken, Twan; Caiment, Florian
细胞生物学
单细胞
发表日期：2026
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Review of Transcriptomic Biomarkers That Predict In Vitro Genotoxicity in Human Cell Lines

预测人类细胞系体外遗传毒性的转录组学生物标志物综述

期刊:Environmental and Molecular Mutagenesis
影响因子:2.3
doi:10.1002/em.70004
Li, Heng-Hong; Aubrecht, Jiri; Doktorova, Tatyana Y; Jennen, Danyel; Corton, J Christopher; Froetschl, Roland; Mezencev, Roman; Yauk, Carole L
细胞生物学
毒理研究
Human
发表日期：2025
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Consensus findings of an International Workshops on Genotoxicity Testing workshop on using transcriptomic biomarkers to predict genotoxicity

关于利用转录组学生物标志物预测遗传毒性的国际遗传毒性测试研讨会的共识性结论

期刊:Environmental and Molecular Mutagenesis
影响因子:2.3
doi:10.1002/em.22645
Froetschl, Roland; Corton, J Christopher; Li, Henghong; Aubrecht, Jiri; Auerbach, Scott S; Caiment, Florian; Doktorova, Tatyana Y; Fujita, Yurika; Jennen, Danyel; Koyama, Naoki; Meier, Matthew J; Mezencev, Roman; Recio, Leslie; Suzuki, Takayoshi; Yauk, Carole L
毒理研究
发表日期：2025
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Outcome of IWGT workshop on transcriptomic biomarkers for genotoxicity: Key considerations for bioinformatics

国际基因毒性转录组学生物标志物研讨会成果：生物信息学的关键考量

期刊:Environmental and Molecular Mutagenesis
影响因子:2.3
doi:10.1002/em.22644
Meier, Matthew J; Caiment, Florian; Corton, J Christopher; Frötschl, Roland; Fujita, Yurika; Jennen, Danyel; Mezencev, Roman; Yauk, Carole
毒理研究
发表日期：2025
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Unraveling the mechanisms underlying drug-induced cholestatic liver injury: identifying key genes using machine learning techniques on human in vitro data sets

揭示药物诱导胆汁淤积性肝损伤的潜在机制：利用机器学习技术对人类体外数据集进行关键基因鉴定

期刊:Archives of Toxicology
影响因子:6.9
doi:10.1007/s00204-023-03583-4
Jiang, Jian; van Ertvelde, Jonas; Ertaylan, Gökhan; Peeters, Ralf; Jennen, Danyel; de Kok, Theo M; Vinken, Mathieu
肝损伤
毒理研究
发表日期：2023
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Reply to Kaminski, N.E.; Cohen, S.M. Comment on "Bischoff et al. The Effects of the Food Additive Titanium Dioxide (E171) on Tumor Formation and Gene Expression in the Colon of a Transgenic Mouse Model for Colorectal Cancer. Nanomaterials 2022, 12, 1256"

回复 Kaminski, NE; Cohen, SM 对“Bischoff 等人，《食品添加剂二氧化钛 (E171) 对结直肠癌转基因小鼠模型结肠肿瘤形成和基因表达的影响》，《纳米材料》2022, 12, 1256”的评论

期刊:Nanomaterials
影响因子:4.3
doi:10.3390/nano13091552
Bischoff, Nicolaj S; Proquin, Héloïse; Jetten, Marlon J; Schrooders, Yannick; Jonkhout, Marloes C M; Briedé, Jacco J; van Breda, Simone G; Jennen, Danyel G J; Medina-Reyes, Estefany I; Delgado-Buenrostro, Norma L; Chirino, Yolanda I; van Loveren, Henk; de Kok, Theo M
Mouse
肿瘤
肠癌
肿瘤免疫
发表日期：2023
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Correction: Bischoff et al. The Effects of the Food Additive Titanium Dioxide (E171) on Tumor Formation and Gene Expression in the Colon of a Transgenic Mouse Model for Colorectal Cancer. Nanomaterials 2022, 12, 1256

更正：Bischoff 等人，《食品添加剂二氧化钛 (E171) 对结直肠癌转基因小鼠模型结肠肿瘤形成和基因表达的影响》，纳米材料 2022, 12, 1256

期刊:Nanomaterials
影响因子:4.3
doi:10.3390/nano13212888
Bischoff, Nicolaj S; Proquin, Héloïse; Jetten, Marlon J; Schrooders, Yannick; Jonkhout, Marloes C M; Briedé, Jacco J; van Breda, Simone G; Jennen, Danyel G J; Medina-Reyes, Estefany I; Delgado-Buenrostro, Norma L; Chirino, Yolanda I; van Loveren, Henk; de Kok, Theo M
Mouse
肿瘤
肠癌
肿瘤免疫
发表日期：2023
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A dynamic model of the intestinal epithelium integrates multiple sources of preclinical data and enables clinical translation of drug-induced toxicity

肠上皮的动态模型整合了多种临床前数据来源，并实现了药物诱导毒性的临床转化。

期刊:Cpt-Pharmacometrics & Systems Pharmacology
影响因子:3
doi:10.1002/psp4.13029
Gall, Louis; Jardi, Ferran; Lammens, Lieve; Piñero, Janet; Souza, Terezinha M; Rodrigues, Daniela; Jennen, Danyel G J; de Kok, Theo M; Coyle, Luke; Chung, Seung-Wook; Ferreira, Sofia; Jo, Heeseung; Beattie, Kylie A; Kelly, Colette; Duckworth, Carrie A; Pritchard, D Mark; Pin, Carmen
毒理研究
发表日期：2023
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Application of transfer learning to predict drug-induced human in vivo gene expression changes using rat in vitro and in vivo data

应用迁移学习方法，利用大鼠体外和体内数据预测药物诱导的人体体内基因表达变化。

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0292030
O'Donovan, Shauna D; Cavill, Rachel; Wimmenauer, Florian; Lukas, Alexander; Stumm, Tobias; Smirnov, Evgueni; Lenz, Michael; Ertaylan, Gokhan; Jennen, Danyel G J; van Riel, Natal A W; Driessens, Kurt; Peeters, Ralf L M; de Kok, Theo M C M
Rat
发表日期：2023
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Transcriptomic Analysis in Human 3D Skin Model Injected with Resorbable Hyaluronic Acid Fillers Reveals Foreign Body Response

对注射可吸收透明质酸填充剂的人体3D皮肤模型进行转录组分析，揭示了异物反应

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms232113046
Jennen, Danyel G J; van Herwijnen, Marcel; Jetten, Marlon; Vandebriel, Rob J; Keizers, Peter; Geertsma, Robert E; de Jong, Wim H; Kleinjans, Jos C S
3D/类器官
Human
发表日期：2022
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