Epithelial GREMLIN1 disrupts intestinal epithelial-mesenchymal crosstalk to induce a wnt-dependent ectopic stem cell niche through stromal remodelling.
上皮细胞 GREMLIN1 通过基质重塑破坏肠道上皮-间质细胞间的相互作用，从而诱导 Wnt 依赖性异位干细胞微环境
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-60364-6
Mulholland Eoghan J, Belnoue-Davis Hayley L, Valbuena Gabriel N, Gunduz Nuray, Ligeza Amelia, Lin Muyang, Biswas Sujata, Gil Vasquez Ester, Omwenga Sulochana, Nasreddin Nadia, Hodder Michael C, Wang Lai Mun, Ng Aik Seng, Jennings Elizabeth, Midwood Kim S, Dedi Neesha, Irshad Shazia, Ridgway Rachel A, Phesse Toby J, East James, Tomlinson Ian Pm, Davies Gareth Cg, Sansom Owen J, Leedham Simon J
