日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Transcriptional competence defines the heterochromatin nucleating potential of isolated MSR units.

转录能力决定了分离的 MSR 单元的异染色质成核潜力。

Lo Yi-Hsuan, Shukeir Nicholas, Erikson Galina, Edupuganti Raghu Ram, Ching Reagan, Puri Deepika, Jerabek Lisa, Shiekhattar Ramin, Jenuwein Thomas

The basic domain of Suv39h2 buffers mitoxantrone-induced heterochromatin destabilization

Suv39h2 的基本结构域缓冲米托蒽醌诱导的异染色质不稳定化

Świst-Rosowska, Kalina M; Ching, Reagan W; Koschorz, Birgit; Galan, Carmen; Engist, Bettina; Jenuwein, Thomas

Forced expression of MSR repeat transcripts above a threshold limit breaks heterochromatin organisation.

MSR重复转录本的强制表达超过阈值会破坏异染色质组织

Ching Reagan W, Świst-Rosowska Kalina M, Erikson Galina, Koschorz Birgit, Engist Bettina, Jenuwein Thomas

The isoflavone genistein selectively stimulates major satellite repeat transcription in mouse heterochromatin.

异黄酮染料木素选择性地刺激小鼠异染色质中的主要卫星重复序列转录

Fuhrmann Thomas, Shukeir Nicholas, W Ching Reagan, Erikson Galina, Dou Yuan, Sawitzki Zoe, Onishi-Seebacher Megumi, Galan Carmen, Jenuwein Thomas

H1 linker histones silence repetitive elements by promoting both histone H3K9 methylation and chromatin compaction

H1连接组蛋白通过促进组蛋白H3K9甲基化和染色质压缩来沉默重复序列。

Healton, Sean E; Pinto, Hugo D; Mishra, Laxmi N; Hamilton, Gregory A; Wheat, Justin C; Swist-Rosowska, Kalina; Shukeir, Nicholas; Dou, Yali; Steidl, Ulrich; Jenuwein, Thomas; Gamble, Matthew J; Skoultchi, Arthur I

H3K9me3-heterochromatin loss at protein-coding genes enables developmental lineage specification

蛋白质编码基因处H3K9me3异染色质的丢失促进发育谱系的分化。

Nicetto, Dario; Donahue, Greg; Jain, Tanya; Peng, Tao; Sidoli, Simone; Sheng, Lihong; Montavon, Thomas; Becker, Justin S; Grindheim, Jessica M; Blahnik, Kimberly; Garcia, Benjamin A; Tan, Kai; Bonasio, Roberto; Jenuwein, Thomas; Zaret, Kenneth S

G9a and Glp methylate lysine 373 in the tumor suppressor p53

G9a 和 Glp 甲基化肿瘤抑制因子 p53 中的赖氨酸 373

Huang, Jing; Dorsey, Jean; Chuikov, Sergei; Zhang, Xinyue; Jenuwein, Thomas; Reinberg, Danny; Berger, Shelley L

Satb1 and Satb2 regulate embryonic stem cell differentiation and Nanog expression

Satb1和Satb2调控胚胎干细胞分化和Nanog表达

Savarese, Fabio; Dávila, Amparo; Nechanitzky, Robert; De La Rosa-Velazquez, Inti; Pereira, Carlos F; Engelke, Rudolf; Takahashi, Keiko; Jenuwein, Thomas; Kohwi-Shigematsu, Terumi; Fisher, Amanda G; Grosschedl, Rudolf

H3K27me3 forms BLOCs over silent genes and intergenic regions and specifies a histone banding pattern on a mouse autosomal chromosome

H3K27me3 在沉默基因和基因间区形成 BLOC,并决定小鼠常染色体上的组蛋白带型模式。

Pauler, Florian M; Sloane, Mathew A; Huang, Ru; Regha, Kakkad; Koerner, Martha V; Tamir, Ido; Sommer, Andreas; Aszodi, Andras; Jenuwein, Thomas; Barlow, Denise P

Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins

组蛋白赖氨酸甲基转移酶 G9a/KMT1C 和含 Jumonji 结构域的 JMJD2/KDM4 蛋白对组蛋白 H1 同工型 4 的动态甲基化和去甲基化

Trojer, Patrick; Zhang, Jin; Yonezawa, Masato; Schmidt, Andreas; Zheng, Haiyan; Jenuwein, Thomas; Reinberg, Danny