Discovery of Macrocyclic Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors that Demonstrate Potent Cellular Efficacy and In Vivo Activity in a Mouse Solid Tumor Xenograft Model
发现具有强效细胞活性和在小鼠实体瘤异种移植模型中体内活性的巨环髓系细胞白血病1 (Mcl-1) 抑制剂
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c01376
Tarr, James C; Jeon, Kyuok; Veerasamy, Nagarathanam; Aichinger, Martin; Salovich, James M; Zhao, Bin; Sensintaffar, John L; Arnhof, Heribert; Wunberg, Tobias; Sgubin, Danielle; Arnold, Allison; Vekariya, Rakesh H; Christov, Plamen P; Kim, Kwangho; Fuchs, Julian Emanuel; Karier, Pol; Betzemeier, Bodo; Van Meveren, Mayme; Miriyala, Nagaraju; Olejniczak, Edward T; Engelhardt, Harald; Lee, Taekyu; McConnell, Darryl; Fesik, Stephen W
