日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Smac mimetic combined with eCD4-Ig reverses latency without reducing SHIV reservoirs in rhesus macaques

Smac 模拟物与 eCD4-Ig 联合使用可逆转恒河猴的潜伏感染,且不减少 SHIV 病毒库。

Pache, Lars; Bui, John K; Klouser, Lindsay M; Fennessey, Christine M; Noyola, Alexander C; Einhaus, Teresa; Zhu, Haiying; Stensland, Laurence; Leguizamo, Isai; Koroma, Abubakarr A; Teriete, Peter; Chang, W L William; Hyrien, Ollivier; Duggan, Natasha N; Heimann, Dominik; Pérez-Osorio, Ailyn C; Bar, Katharine J; Cosford, Nicholas Dp; Keele, Brandon F; Hartigan-O'Connor, Dennis J; Farzan, Michael; Gardner, Matthew R; Jerome, Keith R; Chanda, Sumit K; Kiem, Hans-Peter; Peterson, Christopher W

Respiratory Virus Infections and Pulmonary Impairment After Allogeneic Hematopoietic Cell Transplantation

异基因造血干细胞移植后呼吸道病毒感染和肺功能损害

Cheng, Guang-Shing; Campbell, Angela P; Xie, Hu; Ogimi, Chikara; Waghmare, Alpana; Kuypers, Jane; Nichols, W Garrett; Carpenter, Paul; Corey, Lawrence; Callais, Cheryl; Sandmaier, Brenda M; Stevens-Ayers, Terry; Jerome, Keith R; Chien, Jason W; Leisenring, Wendy M; Englund, Janet A; Boeckh, Michael

Genital herpes shedding episodes associate with altered spatial organization and activation of mucosal immune cells

生殖器疱疹病毒脱落期与黏膜免疫细胞的空间组织改变和激活有关。

MacLean, Finn; Zemek, Rachael M; Tsegaye, Adino Tesfahun; Graham, Jessica B; Swarts, Jessica L; Vick, Sarah C; Potchen, Nicole B; Cruz Talavera, Irene; Warrier, Lakshmi; Dubrulle, Julien; Schroeder, Lena K; Elz, Anna; Sowerby, David; Saito, Ayumi; Thomas, Katherine K; Mack, Matthias; Schiffer, Joshua T; McClelland, R Scott; Jerome, Keith R; Chohan, Bhavna H; Ngure, Kenneth; Mugo, Nelly Rwamba; Newell, Evan W; Lingappa, Jairam R; Lund, Jennifer M

Pooled CAR-T screening in pig-tailed macaques identifies designs with enhanced proliferation, trafficking, and persistence

在豚尾猕猴中进行的混合 CAR-T 筛选鉴定出具有增强的增殖、迁移和持久性的设计。

Maynard, Lucy H; Cavanaugh, Eric J; Zhu, Haiying; Starke, Carly E; Doherty, Sarah M; Einhaus, Teresa; Pérez-Osorio, Ailyn C; Stensland, Laurence; Blair, Cameron; Roche, Aoife M; Everett, John K; Murnane, Robert D; Hoffman, Michelle; Nelson, Veronica; Herrin, Sarah; Littlewood, Chad; Camou, Kaycee; Wilson, Erica; Wessel, Christopher; Bushman, Frederic D; Jerome, Keith R; Kiem, Hans-Peter; Peterson, Christopher W

Variant mutation G215C in SARS-CoV-2 nucleocapsid enhances viral infection via altered genomic encapsidation.

SARS-CoV-2 核衣壳中的变异突变 G215C 通过改变基因组包装增强病毒感染

Kubinski Hannah C, Despres Hannah W, Johnson Bryan A, Schmidt Madaline M, Jaffrani Sara A, Turner Allyson H, Fanuele Conor D, Mills Margaret G, Lokugamage Kumari G, Dumas Caroline M, Shirley David J, Estes Leah K, Pekosz Andrew, Crothers Jessica W, Roychoudhury Pavitra, Greninger Alexander L, Jerome Keith R, Di Genova Bruno Martorelli, Walker David H, Ballif Bryan A, Ladinsky Mark S, Bjorkman Pamela J, Menachery Vineet D, Bruce Emily A

The impact of CMV reactivation on mortality after chimeric antigen receptor T-cell therapy

巨细胞病毒再激活对嵌合抗原受体T细胞疗法后死亡率的影响

Kampouri, Eleftheria; Flaherty, Patrick; Xie, Hu; Sekhon, Mandeep K; Chalal, Clementine; Stevens-Ayers, Terry L; Green, Damian J; Gauthier, Jordan; Shadman, Mazyar; Pérez-Osorio, Ailyn C; Jerome, Keith R; Leisenring, Wendy M; Boeckh, Michael J; Hill, Joshua A

Protection of CD33-modified hematopoietic stem cell progeny from CD33-directed CAR T cells in rhesus macaques

在恒河猴中保护CD33修饰的造血干细胞后代免受CD33靶向CAR T细胞的攻击

Petty, Nicholas E; Radtke, Stefan; Kanestrom, Greta; Fields, Emily; Humbert, Olivier; Fiorenza, Salvatore; Llewellyn, Mallory J; Laszlo, George S; Thomas, Justin; Burger, Zach; Swing, Kyle; Zhu, Haiying; Jerome, Keith R; Turtle, Cameron J; Walter, Roland B; Kiem, Hans-Peter

Serum factors create species-specific barriers to hepatic gene transfer by lipid nanoparticles in liver-humanized mice.

在肝脏人源化小鼠中,血清因子对脂质纳米颗粒介导的肝脏基因转移形成物种特异性屏障

Stone Daniel, Takeuchi Ryo, Dulin Harrison, Loprieno Michelle A, Strongin Daniel E, Sathees Saraswathi, Cradick Thomas J, Aubert Martine, Roychoudhury Pavitra, Gordon Jennifer, Jerome Keith R

Adeno-associated virus vectors and neurotoxicity-lessons from preclinical and human studies

腺相关病毒载体与神经毒性——来自临床前和人体研究的教训

Stone, Daniel; Aubert, Martine; Jerome, Keith R

Cytomegalovirus Viral Load Continues to Predict Poor Outcomes in Adults and Children Despite Improved Hematopoietic Cell Transplantation Success

尽管造血干细胞移植的成功率有所提高,但巨细胞病毒载量仍然是预测成人和儿童预后不良的重要指标。

Sadowska-Klasa, Alicja; Xie, Hu; Zamora, Danniel; Waghmare, Alpana; Hill, Joshua A; Duke, Elizabeth R; Green, Margaret L; Oshima, Masumi Ueda; Sandmaier, Brenda M; Jerome, Keith R; Leisenring, Wendy M; Boeckh, Michael