日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Reduced calcium levels and accumulation of abnormal insulin granules in stem cell models of HNF1A deficiency

HNF1A 缺乏的干细胞模型中钙水平降低和异常胰岛素颗粒的积累

Bryan J González, Haoquan Zhao, Jacqueline Niu, Damian J Williams, Jaeyop Lee, Chris N Goulbourne, Yuan Xing, Yong Wang, Jose Oberholzer, Maria H Blumenkrantz, Xiaojuan Chen, Charles A LeDuc, Wendy K Chung, Henry M Colecraft, Jesper Gromada, Yufeng Shen, Robin S Goland, Rudolph L Leibel, Dieter Egli

Angiopoietin-like protein 3 governs LDL-cholesterol levels through endothelial lipase-dependent VLDL clearance

血管生成素样蛋白 3 通过内皮脂肪酶依赖性 VLDL 清除来调节 LDL 胆固醇水平

Rene C Adam, Ivory J Mintah, Corey A Alexa-Braun, Lisa M Shihanian, Joseph S Lee, Poulabi Banerjee, Sara C Hamon, Hye In Kim, Jonathan C Cohen, Helen H Hobbs, Cristopher Van Hout, Jesper Gromada, Andrew J Murphy, George D Yancopoulos, Mark W Sleeman, Viktoria Gusarova

Discordance between GLP-1R gene and protein expression in mouse pancreatic islet cells

小鼠胰岛细胞GLP-1R基因与蛋白表达的不一致

Sarah M Gray, Yurong Xin, Elizabeth C Ross, Bryanna M Chazotte, Megan E Capozzi, Kimberley El, Berit Svendsen, Peter Ravn, Kyle W Sloop, Jenny Tong, Jesper Gromada, Jonathan E Campbell, David A D'Alessio

Hepatic Glucagon Signaling Regulates PCSK9 and Low-Density Lipoprotein Cholesterol

肝脏胰高血糖素信号调节 PCSK9 和低密度脂蛋白胆固醇

Stefano Spolitu, Haruka Okamoto, Wen Dai, John A Zadroga, Erika S Wittchen, Jesper Gromada, Lale Ozcan

Preemptive Activation of the Integrated Stress Response Protects Mice From Diet-Induced Obesity and Insulin Resistance by Fibroblast Growth Factor 21 Induction

通过成纤维细胞生长因子 21 诱导预先激活综合应激反应可保护小鼠免于饮食引起的肥胖和胰岛素抵抗

Xu Xu, Christopher Krumm, Jae-Seon So, Curtis J Bare, Corey Holman, Jesper Gromada, David E Cohen, Ann-Hwee Lee

Glucagon contributes to liver zonation

胰高血糖素有助于肝脏分区

Xiping Cheng, Sun Y Kim, Haruka Okamoto, Yurong Xin, George D Yancopoulos, Andrew J Murphy, Jesper Gromada

Mice harboring the human SLC30A8 R138X loss-of-function mutation have increased insulin secretory capacity

携带人类 SLC30A8 R138X 功能丧失突变的小鼠胰岛素分泌能力增强

Sandra Kleiner, Daniel Gomez, Bezawit Megra, Erqian Na, Ramandeep Bhavsar, Katie Cavino, Yurong Xin, Jose Rojas, Giselle Dominguez-Gutierrez, Brian Zambrowicz, Gaelle Carrat, Pauline Chabosseau, Ming Hu, Andrew J Murphy, George D Yancopoulos, Guy A Rutter, Jesper Gromada

Amino Acid Transporter Slc38a5 Controls Glucagon Receptor Inhibition-Induced Pancreatic α Cell Hyperplasia in Mice

氨基酸转运蛋白Slc38a5控制小鼠胰高血糖素受体抑制诱导的胰腺α细胞增生

Jinrang Kim, Haruka Okamoto, ZhiJiang Huang, Guillermo Anguiano, Shiuhwei Chen, Qing Liu, Katie Cavino, Yurong Xin, Erqian Na, Rachid Hamid, Joseph Lee, Brian Zambrowicz, Roger Unger, Andrew J Murphy, Yan Xu, George D Yancopoulos, Wen-Hong Li, Jesper Gromada

Activin A more prominently regulates muscle mass in primates than does GDF8

激活素 A 对灵长类动物肌肉质量的调节作用比 GDF8 更显著

Esther Latres, Jason Mastaitis, Wen Fury, Lawrence Miloscio, Jesus Trejos, Jeffrey Pangilinan, Haruka Okamoto, Katie Cavino, Erqian Na, Angelos Papatheodorou, Tobias Willer, Yu Bai, Jee Hae Kim, Ashique Rafique, Stephen Jaspers, Trevor Stitt, Andrew J Murphy, George D Yancopoulos, Jesper Gromada

Inflammatory Ly6Chi monocytes and their conversion to M2 macrophages drive atherosclerosis regression

炎症性Ly6Chi单核细胞及其向M2巨噬细胞的转化驱动动脉粥样硬化消退

Karishma Rahman ,Yuliya Vengrenyuk ,Stephen A Ramsey ,Noemi Rotllan Vila ,Natasha M Girgis ,Jianhua Liu ,Viktoria Gusarova ,Jesper Gromada ,Ada Weinstock ,Kathryn J Moore ,P'ng Loke ,Edward A Fisher